Sharov V G, Beskrovnova N N, Vikhert A M, Kryzhanovskiĭ S A, Kaverina N V
Arkh Patol. 1986;48(8):49-56.
Ultrastructural changes of Purkinje cells located on the periphery of the cardiac conductive system (subendocardium and false tendons) were studied in dogs in the presence of ventricular fibrillation developed in 30 minutes after coronary artery ligation. Ventricular fibrillation at the early stages of experimental myocardial infarction was invariably associated with the development of multiple ultrastructural lesions in the conductive Purkinje cells of subendocardium and false tendons. These changes are without any doubt important for the pathogenesis of ventricular fibrillation in myocardial infarction and they possibly take place in cases of sudden cardiac death.
在冠状动脉结扎30分钟后发生心室颤动的犬中,研究了位于心脏传导系统外周(心内膜下和假腱索)的浦肯野细胞的超微结构变化。实验性心肌梗死早期的心室颤动总是与心内膜下和假腱索的传导性浦肯野细胞中多个超微结构病变的发展相关。毫无疑问,这些变化对于心肌梗死中心室颤动的发病机制很重要,并且它们可能在心脏性猝死的病例中发生。