Beskrovnova N N, Sharov V G
Arkh Patol. 1985;47(5):42-8.
Ultrastructure of the myocardium in the experiment was studied just after the heart ventricular fibrillation and 3 h after the animal death; the results were compared to those obtained by studying ultrastructure of human myocardium in patients dying from myocardial infarction complicated by ventricular fibrillation. The similarity of ultrastructural and autolytic changes was revealed in both series of observation. Overcontraction of myofibrils and redistribution of the mitochondria in cardiomyocytes, increase of the sarcoplasmic reticulum vesiculation, oedema of sarcoplasm, structural alterations of intercalative discs, later appearance of the symptoms of the irreversibility of lesions in the mitochondria and early penetration of colloidal lanthanum particles in rigor cells may serve ultrastructural diagnostic symptom of ventricular fibrillation. A better preservation of Purkinje's cells as compared to the contractile cardiomyocytes is also demonstrated.
在实验中，于心室颤动刚发生后以及动物死亡3小时后对心肌超微结构进行了研究；将结果与通过研究死于心肌梗死并发心室颤动患者的人心肌超微结构所获得的结果进行了比较。在这两组观察中均发现了超微结构和自溶变化的相似性。肌原纤维过度收缩以及心肌细胞中线粒体重新分布、肌浆网小泡化增加、肌浆水肿、闰盘结构改变、线粒体损伤不可逆症状出现较晚以及镧系胶体颗粒在强直收缩细胞中早期渗透等情况，可作为心室颤动的超微结构诊断症状。同时还表明，与收缩性心肌细胞相比，浦肯野细胞保存得更好。
