确保苄星青霉素的供应：预防未来短缺的全球风险和缓解策略。
Securing the supply of benzathine penicillin: a global perspective on risks and mitigation strategies to prevent future shortages.
机构信息
Clinton Health Access Initiative, 383 Dorchester Avenue, Boston, MA 02127, USA.
U.S. Centers for Disease Control and Prevention, Division of HIV Prevention 1600, Clifton Road, Atlanta, GA 30333, USA.
出版信息
Int Health. 2024 May 1;16(3):279-282. doi: 10.1093/inthealth/ihad087.
Benzathine benzylpenicillin is a globally indispensable medicine. As a long-lasting injectable penicillin, it serves as the primary treatment for syphilis, group A streptococcal infections, rheumatic fever and rheumatic heart disease. A competitive market and low profit margins, compounded by limited visibility of demand, have resulted in a decreased number of active pharmaceutical ingredient (API) manufacturers. By 2016, only three Chinese API manufacturers remained, continuing to supply to the global market today. Recurring global shortages, a consequence of supply and demand imbalances, indicate underlying market risks. Therefore, the need for mitigation strategies is imperative.
卞星青霉素是一种全球不可或缺的药物。作为一种长效注射青霉素，它是治疗梅毒、A 组链球菌感染、风湿热和风湿性心脏病的主要药物。竞争激烈的市场和微薄的利润率，再加上需求的可见度有限，导致活性药物成分（API）制造商的数量减少。到 2016 年，仅剩下三家中国 API 制造商，至今仍在向全球市场供应。由于供需失衡导致的全球供应短缺反复出现，表明存在潜在的市场风险。因此，需要采取缓解策略。
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