Maricopa County Department of Public Health, STD Clinic, Phoenix, AZ.
Sex Transm Dis. 2024 Mar 1;51(3):192-198. doi: 10.1097/OLQ.0000000000001921. Epub 2024 Jan 3.
As the incidence of syphilis continues to increase, examining benzathine penicillin G (BPG) treatment data provides valuable insight for public health strategies. This study analyzed the trends of where BPG is administered relative to the initial clinical site of syphilis diagnosis. Our findings are timely in the context of recent national BPG shortages.
The analysis included persons diagnosed with any syphilis stage in Maricopa County, Arizona, from January 1, 2021, to December 31, 2021. The Arizona surveillance database (PRISM) was the source of demographic, testing, and treatment data.
Of a total of 4028 persons with syphilis, 3038 (75.4%) received at least 1 injection of BPG. Among persons who received an initial BPG injection, only 1719 (56.6%) were diagnosed and treated at the same clinical site type. The Maricopa County Sexually Transmitted Disease Clinic administered BPG to 48.8% (n = 1483) of persons with syphilis who received an initial injection.
Our findings analyze trends in BPG administration that are likely due to treatment referral practices and medication cost. Administration of BPG is not guaranteed at the clinical site of diagnosis, highlighting concerns regarding access to BPG. A burden is placed on patients who are required to leave their diagnosing provider to seek syphilis treatment at other health facilities that administer BPG.
随着梅毒发病率的持续上升，检查苄星青霉素 G（BPG）治疗数据为公共卫生策略提供了有价值的见解。本研究分析了 BPG 给药地点与梅毒初始临床诊断地点的趋势。在最近全国 BPG 短缺的背景下，我们的研究结果具有及时性。
该分析包括 2021 年 1 月 1 日至 2021 年 12 月 31 日在亚利桑那州马里科帕县诊断出任何梅毒阶段的患者。亚利桑那州监测数据库（PRISM）是人口统计学、检测和治疗数据的来源。
在总共 4028 名梅毒患者中，有 3038 名（75.4%）至少接受了 1 次 BPG 注射。在接受初始 BPG 注射的患者中，只有 1719 名（56.6%）在同一临床站点类型进行诊断和治疗。马里科帕县性传播疾病诊所为 48.8%（n = 1483）接受初始注射的梅毒患者注射了 BPG。
我们的研究结果分析了 BPG 给药趋势，这可能是由于治疗转诊实践和药物成本所致。在诊断的临床站点不一定能保证 BPG 的给药，这突显了对 BPG 可及性的关注。患者需要离开诊断提供者，到其他管理 BPG 的医疗机构寻求梅毒治疗，这给他们带来了负担。
