Hahn P
Biol Neonate. 1986;50(4):205-13. doi: 10.1159/000242601.
The incorporation of 3H2O into the lipids of brown and white adipose tissue (BAT and WAT), skin, liver, heart, kidney, brain and lungs was studied 1 h after injection in rats aged 1, 13 and 22 days. In the younger age group, triglyceride synthesis was considerably higher in BAT than in any other tissue, while in the 22-day-old rats, this is no longer the case. Cholesterol synthesis in the oldest age group was highest in liver. In the younger animals, there was little difference between tissues in the low rate of cholesterol synthesis except in the brain where the rates of all lipid syntheses were highest on day 13. The surprisingly high rate of triglyceride synthesis in BAT of infant rats is partly due to the high rate of synthesis of the glycerol moiety. Nevertheless, on hydrolysis, the rate of fatty acid synthesis was still highest in these animals.
在1、13和22日龄的大鼠注射后1小时，研究了3H2O掺入棕色和白色脂肪组织（BAT和WAT）、皮肤、肝脏、心脏、肾脏、脑和肺的脂质中的情况。在较年轻的年龄组中，BAT中的甘油三酯合成比任何其他组织都要高得多，而在22日龄的大鼠中，情况不再如此。在最年长的年龄组中，肝脏中的胆固醇合成最高。在较年轻的动物中，除了脑在13日时所有脂质合成速率最高外，各组织中胆固醇合成速率较低，差异不大。幼鼠BAT中甘油三酯合成速率惊人地高，部分原因是甘油部分的合成速率高。然而，水解后，这些动物中脂肪酸合成速率仍然最高。
