Pastor-Anglada M, Remesar X
Biol Res Pregnancy Perinatol. 1986;7(3):134-7.
In the rat, mid-pregnancy seems to be related to an active nitrogen metabolism. In the present work we studied how the plasma homeostasis and the urinary nitrogen excretion of urea and ammonia could be altered during this period. Urea and ammonia plasma levels do not show significant changes, whereas, their urinary excretion is increased at mid-pregnancy. When urea levels in urine are corrected by the urinary creatinine content and the food intake, we found lower values in pregnant than in virgin rats. Thus, the organic nitrogen is more spared during pregnancy than before impregnation without any significant changes in the urea and ammonia plasma concentrations.
在大鼠中,妊娠中期似乎与活跃的氮代谢有关。在本研究中,我们探讨了在此期间血浆稳态以及尿素和氨的尿氮排泄如何变化。血浆中尿素和氨的水平没有显著变化,然而,它们在妊娠中期的尿排泄增加。当用尿肌酐含量和食物摄入量校正尿中尿素水平时,我们发现怀孕大鼠的值低于未孕大鼠。因此,与怀孕前相比,妊娠期间有机氮的保留更多,而血浆中尿素和氨的浓度没有任何显著变化。