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累及脑干和颅外区域的面神经神经淋巴瘤病

Facial Nerve Neurolymphomatosis That Extends to Both the Brainstem and Extracranial Regions.

作者信息

Kondoh Takeshi, Lee Kana, Higashino Masashi, Mizowaki Takashi, Tanaka Hirotomo, Takaishi Yoshiyuki

机构信息

Neurosurgery, Shinsuma General Hospital, Kobe, JPN.

Otolaryngology, Shinsuma General Hospital, Kobe, JPN.

出版信息

Cureus. 2023 Sep 1;15(9):e44551. doi: 10.7759/cureus.44551. eCollection 2023 Sep.

Abstract

A 73-year-old female developed right facial paralysis of House-Brackmann (H-B) grade III and was diagnosed with Bell's palsy. After three months of steroid therapy, she developed progressive hearing loss, and an MRI revealed a tumor in the right internal auditory canal. Within a few months, the right facial nerve palsy recurred, and the patient was treated with Gamma Knife radiosurgery. The tumor in the irradiated region disappeared, but new dysphagia was observed, and a right parotid gland tumor was detected for the first time. Tumors of the right parotid gland and the digastric muscle of the jaw were surgically resected, and a diagnosis of diffuse large B-cell lymphoma was made. The tumor had invaded the cranial nerves and brainstem region, and the patient did not wish to undergo further medical therapy. This was a case of malignant lymphoma that started as facial paralysis and invaded the brainstem, and testing for possible lymphoma at an early stage prior to radiotherapy was desirable.

摘要

一名73岁女性出现House-Brackmann(H-B)Ⅲ级右侧面瘫,被诊断为贝尔麻痹。接受三个月的类固醇治疗后,她出现进行性听力丧失,磁共振成像(MRI)显示右侧内耳道有一个肿瘤。几个月内,右侧面神经麻痹复发,患者接受了伽玛刀放射外科治疗。照射区域的肿瘤消失,但出现了新的吞咽困难,并且首次检测到右侧腮腺肿瘤。手术切除了右侧腮腺和下颌二腹肌的肿瘤,诊断为弥漫性大B细胞淋巴瘤。肿瘤已侵犯颅神经和脑干区域,患者不希望接受进一步的药物治疗。这是一例始于面瘫并侵犯脑干的恶性淋巴瘤病例,在放疗前早期检测可能的淋巴瘤是可取的。

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