Shukla Ashish Kumar, Morya Vinod, Datta Bhaskar
Department of Biological Engineering, Indian Institute of Technology Gandhinagar Gandhinagar 382055 India
Department of Chemistry, Indian Institute of Technology Gandhinagar Gandhinagar 382055 India
RSC Adv. 2023 Oct 2;13(41):28767-28772. doi: 10.1039/d3ra05411j. eCollection 2023 Sep 26.
The ability of bacteria to facilitate fabrication of nanomaterials has been adapted towards bacterial sensing applications. In this work, we fabricate spherical, cubic and truncated octahedron topologies of CuO nanoparticles -facilitated redox reaction in an electrochemical setup. The CuO nanoparticles exhibit cytochrome c oxidase-like activity with the spherical topology displaying higher catalytic rate compared to the other geometries. The topology-dependent catalytic behavior of CuO nanoparticles has not been reported previously. The CuO nanozymes also display killing activity in a topology-correlated manner. The mediated redox reaction in an electrochemical setup is being reported for the first time for synthesis of different topologies of CuO which also exert a variable antibacterial effect.
细菌促进纳米材料制造的能力已被应用于细菌传感领域。在这项工作中，我们在电化学装置中制备了球形、立方体形和截角八面体形拓扑结构的CuO纳米颗粒，以促进氧化还原反应。CuO纳米颗粒表现出细胞色素c氧化酶样活性，其中球形拓扑结构的催化速率高于其他几何形状。此前尚未报道过CuO纳米颗粒的拓扑依赖性催化行为。CuO纳米酶还以与拓扑相关的方式表现出杀菌活性。首次报道了在电化学装置中通过介导的氧化还原反应合成不同拓扑结构的CuO，这些CuO也具有不同的抗菌效果。
