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在中非共和国姆拜基地区开展雅司病监测。

Prospecting for yaws in the Mbaïki Health District in the Central African Republic.

机构信息

Doctoral School of Human and Veterinary Health Sciences, University of Bangui, Bangui, Central African Republic.

Department of Public Health, Faculty of Health Sciences, University of Bangui, Bangui, Central African Republic.

出版信息

Pan Afr Med J. 2023 Jul 12;45:121. doi: 10.11604/pamj.2023.45.121.34060. eCollection 2023.

Abstract

INTRODUCTION

yaws is endemic in the Central African Republic. The last cases of yaws notified by CAR to WHO date back to 2012. The objective of this study was to measure the prevalence of yaws in the health district of Mbaïki and to describe its clinical and epidemiological characteristics.

METHODS

this is a descriptive cross-sectional study, conducted from April 10 to 18, 2020 in the Mbaïki health district. Yaws cases were sought in 570 households in the 38 selected villages of the district. Any consenting individual over the age of one year with yaws-like skin lesions was a suspected case of yaws and included in the study. Blood was taken from suspected cases for serological testing (TDR, RPR and TPHA). Any suspected case of yaws with positive RPR and TPHA was considered a confirmed case.

RESULTS

a total of 1967 people were examined, of whom 113 were considered suspected cases of yaws. All suspected cases were RPR-positive, 41 TPHA-positive and 13 RDT-positive. Forty-one cases of yaws were confirmed in 18 (47.37%) villages. The prevalence of yaws in the Mbaïki health district was 2.08%. Among the cases, 38.94% were children aged 1 to 14. The sex ratio was 1.69. Lesions clinically suggestive of yaws were papilloma-like in 77.00% of cases, followed by micropapules (8.00%) and ulcerations (5.00%).

CONCLUSION

eight of the nine communes in the Mbaïki health district are yaws-endemic. This result suggests the need to implement the Morges strategy in the Mbaïki health district.

摘要

简介

雅司病在中非共和国流行。中非共和国上一次向世界卫生组织报告雅司病病例是在 2012 年。本研究的目的是测量 Mbaïki 卫生区的雅司病流行率,并描述其临床和流行病学特征。

方法

这是一项描述性的横断面研究,于 2020 年 4 月 10 日至 18 日在 Mbaïki 卫生区进行。在该地区的 38 个选定村庄中,对 570 户家庭进行了雅司病病例搜索。任何年龄在一岁以上且具有雅司病样皮肤损伤的同意者均被视为雅司病疑似病例,并纳入研究。从疑似病例中采集血液进行血清学检测(TDR、RPR 和 TPHA)。任何 RPR 和 TPHA 阳性的疑似雅司病病例均被视为确诊病例。

结果

共检查了 1967 人,其中 113 人被认为是雅司病疑似病例。所有疑似病例均为 RPR 阳性,41 例 TPHA 阳性,13 例 RDT 阳性。在 18 个(47.37%)村庄中确诊了 41 例雅司病病例。Mbaïki 卫生区的雅司病流行率为 2.08%。在这些病例中,38.94%是 1 至 14 岁的儿童。性别比为 1.69。临床上提示雅司病的病变 77.00%为乳头状,其次是微丘疹(8.00%)和溃疡(5.00%)。

结论

Mbaïki 卫生区的 9 个公社中有 8 个是雅司病流行区。这一结果表明,有必要在 Mbaïki 卫生区实施莫尔日战略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d204/10543901/0cd6a28386e1/PAMJ-45-121-g001.jpg

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