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[中非共和国雅司病的再度流行。俾格米人作为病毒宿主的作用]

[Resurgence of yaws in Central African Republic. Role of the Pygmy population as a reservoir of the virus].

作者信息

Hervé V, Kassa Kelembho E, Normand P, Georges A, Mathiot C, Martin P

机构信息

Institut Pasteur, Bangui, République centrafricaine.

出版信息

Bull Soc Pathol Exot. 1992;85(5):342-6.

PMID:1292791
Abstract

The authors present the results of a clinical (framboesia) and serological (TPHA and VDRL) investigation aimed at defining the reservoir of virus of yaws in the Lobaye area (southwest of CAR) out of which the disease spreads in spite of previous mass treatment campaigns. The Lobaye focus is still active because we found among the pediatric population under the age of 15 years, 5.6% contagious skin lesion and 19.6% VDRL+. In this area with contact between nomadic Pygmies and sedentary ethnic groups, the observed level of clinical and serological attacks suggested that the pygmie population, as previously described, makes up the principal focus of yaws. For every 1 case found through clinical examination, 3.5 cases VDRL+ and 4.8 cases TPHA+ are found through serological examination. This proportion indicates that clinical screening alone is not sufficient to evaluate the endemic yaws level in a population.

摘要

作者介绍了一项临床(雅司病)和血清学(梅毒螺旋体血细胞凝集试验和性病研究实验室玻片试验)调查的结果,该调查旨在确定洛巴耶地区(中非共和国西南部)雅司病毒的储存宿主,尽管此前开展了大规模治疗运动,但该疾病仍在该地区传播。洛巴耶疫源地仍然活跃,因为我们在15岁以下的儿童人群中发现,5.6%有传染性皮肤病变,19.6%性病研究实验室玻片试验呈阳性。在这个游牧俾格米人与定居民族有接触的地区,观察到的临床和血清学感染水平表明,如先前所述,俾格米人群构成了雅司病的主要疫源地。通过临床检查每发现1例病例,通过血清学检查可发现3.5例性病研究实验室玻片试验呈阳性病例和4.8例梅毒螺旋体血细胞凝集试验呈阳性病例。这一比例表明,仅靠临床筛查不足以评估人群中雅司病的流行程度。

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