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大血管中血流与血细胞比容关系的变化

Changes in blood flow: hematocrit relationship in larger blood vessels.

作者信息

Mchedlishvili G, Varazashvili M

出版信息

Biorheology. 1986;23(4):385-93. doi: 10.3233/bir-1986-23407.

DOI:10.3233/bir-1986-23407
PMID:3779063
Abstract

We assessed the red blood cell concentration (by estimating the cell number and hematocrit) in blood samples taken from the rabbit common carotid artery. This parameter was found to be dependent upon the blood flow velocity in the artery: reduction of the velocity to mean 62% of the initial value (100%), produced by partial obstruction of the artery, resulted in the decrease of red cell concentration by 1/4 to 1/7, despite the same systemic arterial pressure level and absence of appreciable changes in the blood taken from the control (contralateral) carotid artery. The relationship of the red cell number and hematocrit in the carotid artery was linear (r = 0.76). We conclude therefore, that changes in the local blood flow: hematocrit relationship induced by separation of red cells and plasma in vascular bifurcations occur not only in the microvascular beds, but in the entire arterial branching sequence, including the largest arteries.

摘要

我们评估了从兔颈总动脉采集的血样中的红细胞浓度(通过估算细胞数量和血细胞比容)。发现该参数取决于动脉中的血流速度:动脉部分阻塞导致血流速度降至初始值(100%)的平均62%,尽管全身动脉压水平相同且对照(对侧)颈动脉采集的血液无明显变化,但红细胞浓度仍降低了1/4至1/7。颈动脉中红细胞数量与血细胞比容的关系呈线性(r = 0.76)。因此,我们得出结论,血管分叉处红细胞与血浆分离所引起的局部血流:血细胞比容关系的变化不仅发生在微血管床,而且发生在整个动脉分支序列,包括最大的动脉。

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1
Changes in blood flow: hematocrit relationship in larger blood vessels.大血管中血流与血细胞比容关系的变化
Biorheology. 1986;23(4):385-93. doi: 10.3233/bir-1986-23407.
2
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