Mitala Yekosani, Ssenkumba Brian, Nabulya Rita, Kitenda Francis Nsumba, Tumwesigye Habert, Birungi Abraham, Dratu Chau Richard, Mushabe Branchard, Baker Nichole, Atwine Raymond
Department of Pathology, Mbarara University of Science and Technology, Mbarara City, Uganda.
Department of Pediatrics, Mbarara Regional Referral Hospital, Mbarara City, Uganda.
Cancer Manag Res. 2023 Sep 26;15:1047-1052. doi: 10.2147/CMAR.S426780. eCollection 2023.
Primary breast Burkitt lymphoma is extremely rare. Commonly endemic Burkitt lymphoma presents with abdominal, jaw, periorbital, or genitourinary mass.
We report a case of a 16-year-old girl with rapidly enlarging left breast swelling associated with evening fevers. This was later confirmed to be stage 1 primary breast Burkitt lymphoma involving the left breast. This represents the first described case of primary breast endemic Burkitt lymphoma in Uganda. She was started on chemotherapy and exhibited an impressive response to the drugs.
This case raises awareness of rare sites for endemic Burkitt lymphoma in Uganda. Accurately diagnosing this case was of great importance since it determined the treatment modality (mastectomy or not) which would have an everlasting impact on her life.
原发性乳腺伯基特淋巴瘤极为罕见。常见的地方性伯基特淋巴瘤表现为腹部、颌部、眶周或泌尿生殖系统肿块。
我们报告一例16岁女孩,其左乳迅速肿大并伴有夜间发热。后来确诊为1期原发性乳腺伯基特淋巴瘤,累及左乳。这是乌干达首例描述的原发性乳腺地方性伯基特淋巴瘤病例。她开始接受化疗,对药物表现出显著反应。
该病例提高了对乌干达地方性伯基特淋巴瘤罕见发病部位的认识。准确诊断该病例非常重要,因为它决定了治疗方式(是否进行乳房切除术),这将对她的生活产生持久影响。