Lee Sun Hwa, Oh Jong Seok, Choi Yun Hyung, Lim Ji Yeon
Department of Emergency Medicine, Ewha Womans University Mokdong Medical Center, Ewha Womans University, 911-1 Mokdong, Yangcheon-gu, Seoul 07985, Republic of Korea.
Seoul National University, Economics, 1 Gwanak-ro, Gwanak-gu, Seoul, Republic of Korea.
Emerg Med Int. 2023 Sep 25;2023:8456427. doi: 10.1155/2023/8456427. eCollection 2023.
The aim of this study was to examine the neutrophil-to-lymphocyte ratio (NLR) in patients diagnosed with a deep neck infection (DNI) to identify helpful indicators for the initial differential diagnosis. This study was conducted as a single-center, retrospective cohort study that utilized data from the electronic medical records of patients who visited the emergency department in a tertiary university hospital between February 2018 and April 2022. The study enrolled patients aged ≥18 years who were diagnosed with tonsillitis with or without DNI during the study period. The NLR of patients without DNI was 6.1 ± 5.03, and the NLR of patients with acute tonsillitis with DNI was 8.0 ± 5.67, showing significant differences. The rate of admission in the general wards (GWs) and ICUs was significantly higher in patients with DNI, and the length of hospital stay was also significantly longer in patients with DNI. Older age, male, lower body temperature, C-reactive protein, and NLR were significant independent risk factors for DNI in patients with tonsillitis. The cutoff value for predicting DNI in patients with body temperature <37.5 was 3.09. The NLR of patients with tonsillitis, especially those with normal body temperature, can be used to predict their prognosis.
本研究的目的是检查诊断为深部颈部感染（DNI）的患者的中性粒细胞与淋巴细胞比率（NLR），以确定有助于初始鉴别诊断的指标。本研究作为一项单中心回顾性队列研究开展，利用了2018年2月至2022年4月期间在一所三级大学医院急诊科就诊的患者电子病历数据。该研究纳入了年龄≥18岁、在研究期间被诊断为患有或未患有DNI的扁桃体炎患者。未患DNI患者的NLR为6.1±5.03，患有急性扁桃体炎合并DNI患者的NLR为8.0±5.67，差异有统计学意义。DNI患者在普通病房（GWs）和重症监护病房（ICU）的住院率显著更高，DNI患者的住院时间也显著更长。年龄较大、男性、体温较低、C反应蛋白和NLR是扁桃体炎患者发生DNI的显著独立危险因素。体温<37.5的患者预测DNI的临界值为3.09。扁桃体炎患者的NLR，尤其是体温正常的患者，可用于预测其预后。
