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管理式医疗组织中2型糖尿病患者的白蛋白尿筛查

Albuminuria Screening in People With Type 2 Diabetes in a Managed Care Organization.

作者信息

Keong Farrah, Gander Jennifer, Wilson Daniel, Durthaler Jeffrey, Pimentel Belkis, Barzilay Joshua I

机构信息

Business Intelligence Group, Kaiser Permanente of Georgia, Atlanta, Georgia.

Center for Research and Evaluation, Kaiser Permanente of Georgia, Atlanta, Georgia.

出版信息

AJPM Focus. 2023 Aug 1;2(4):100133. doi: 10.1016/j.focus.2023.100133. eCollection 2023 Dec.

Abstract

INTRODUCTION

Albuminuria-an increased amount of urine albumin, in milligrams, adjusted for grams of urine creatinine-is an early marker of diabetic kidney disease. Several new classes of medications are now available that effectively lower albuminuria levels with the potential to delay or prevent the progression of diabetic kidney disease. However, screening for albuminuria in the U.S. is low in population-based studies (<10% to ∼50% at most). In this study, we examine whether screening for albuminuria was improved in an integrated model of healthcare delivery following the recommendations of the National Committee for Quality Assurance mandate (an umbrella group for the managed healthcare industry) to screen for albuminuria.

METHODS

We examined screening for albuminuria over a 2-year period among people with Type 2 diabetes in a U.S. HMO with an electronic medical record, onto which automated laboratory ordering for albuminuria could be added when a patient appeared at the laboratory (for any reason) if albuminuria testing had not been obtained within the previous 365 days. Participants under this plan received diabetes education at no cost and panel managers to guide their diabetes care. Logistic regression using data from 2020 and 2021, separately, evaluated the relationship between patient characteristics and the likelihood of albuminuria screening.

RESULTS

There were 20,688 and 22,487 participants with Type 2 diabetes mellitus in 2020 and 2021, respectively, who were analyzed. Approximately 80% were screened for albuminuria in both years. African American participants and those aged >64 years were more likely to have completed albuminuria screening. Screened individuals had lower HbA1c, blood pressure, and low-density lipoprotein cholesterol levels than those who were not screened.

CONCLUSIONS

In an integrated healthcare model, it is possible to achieve consistently high rates of albuminuria screening in people with Type 2 diabetes, especially in groups at high risk for kidney disease.

摘要

引言

尿白蛋白(以毫克为单位,根据尿肌酐克数进行调整后的尿白蛋白含量增加)是糖尿病肾病的早期标志物。目前有几类新型药物可有效降低尿白蛋白水平,有可能延缓或预防糖尿病肾病的进展。然而,在美国基于人群的研究中,尿白蛋白筛查率较低(最多<10%至约50%)。在本研究中,我们根据美国国家质量保证委员会(管理式医疗行业的一个总括组织)筛查尿白蛋白的要求,检验在综合医疗服务模式中尿白蛋白筛查是否得到改善。

方法

我们在美国一家拥有电子病历的健康维护组织中,对2型糖尿病患者进行了为期2年的尿白蛋白筛查检查。如果患者在过去365天内未进行过尿白蛋白检测,当患者出现在实验室(无论何种原因)时,可在该电子病历上添加尿白蛋白自动实验室检测医嘱。该计划下的参与者可免费接受糖尿病教育,并由小组管理人员指导其糖尿病护理。分别使用2020年和2021年的数据进行逻辑回归分析,评估患者特征与尿白蛋白筛查可能性之间的关系。

结果

2020年和2021年分别有20688名和22487名2型糖尿病患者接受分析。两年中约80%的患者进行了尿白蛋白筛查。非裔美国参与者和年龄>64岁的参与者更有可能完成尿白蛋白筛查。接受筛查的个体的糖化血红蛋白、血压和低密度脂蛋白胆固醇水平低于未接受筛查的个体。

结论

在综合医疗模式中,2型糖尿病患者,尤其是肾病高危人群,有可能实现持续的高尿白蛋白筛查率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f4d/10546502/f273f8b1bafa/ga1.jpg

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