Caty A, Cappelaere P, Demaille A
Bull Cancer. 1986;73(1):81-4.
After extensive staging, localized prostate carcinomas are treated by radical prostatectomy, external beam radiation therapy or interstitial radioactive implantation therapy combined or not with external radiation. For these patients, it is not demonstrated that adjuvant hormonotherapy increases survival duration. For metastatic carcinomas, orchiectomy or low dose of DES are possible. When carcinoma patients escape to endocrine treatment, there are given chemotherapy. Hormonal associations with central and peripheral action mechanisms could modify, in early future, present treatment options for advanced carcinomas.
经过广泛分期后,局限性前列腺癌通过根治性前列腺切除术、外照射放疗或间质放射性植入治疗(可联合或不联合外照射)进行治疗。对于这些患者,尚无证据表明辅助激素疗法能延长生存期。对于转移性癌,可进行睾丸切除术或给予低剂量己烯雌酚。当癌症患者对内分泌治疗产生耐药时,则给予化疗。具有中枢和外周作用机制的激素联合应用可能在不久的将来改变晚期癌症目前的治疗选择。