神经调节蛋白-1：治疗心肾综合征的一剂良药？以及对我们所有其他疾病都有效？ - Suppr

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Neuregulin-1: A Tonic for Cardiorenal Syndrome? And All Else That Ails Us?

作者信息

Geissler Andrew K, Sawyer Douglas B

机构信息

Maine Medical Center and MaineHealth, Portland, Maine, USA.

Tufts University School of Medicine, Boston, Massachusetts, USA.

出版信息

JACC Basic Transl Sci. 2023 Sep 25;8(9):1177-1179. doi: 10.1016/j.jacbts.2023.06.002. eCollection 2023 Sep.

DOI:10.1016/j.jacbts.2023.06.002

PMID:37791303

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10544078/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68ee/10544078/84c8419cc917/fx1.jpg

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本文引用的文献

Neuregulin-1β Improves Uremic Cardiomyopathy and Renal Dysfunction in Rats.

JACC Basic Transl Sci. 2023 May 31;8(9):1160-1176. doi: 10.1016/j.jacbts.2023.03.003. eCollection 2023 Sep.

Neuregulins: protective and reparative growth factors in multiple forms of cardiovascular disease.

Clin Sci (Lond). 2020 Oct 16;134(19):2623-2643. doi: 10.1042/CS20200230.

ErbB4 signaling stimulates pro-inflammatory macrophage apoptosis and limits colonic inflammation.

Cell Death Dis. 2017 Feb 23;8(2):e2622. doi: 10.1038/cddis.2017.42.

Indoxyl Sulfate: A Novel Cardiovascular Risk Factor in Chronic Kidney Disease.

J Am Heart Assoc. 2017 Feb 7;6(2):e005022. doi: 10.1161/JAHA.116.005022.

Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and prevention.

Lancet. 2013 Jul 27;382(9889):339-52. doi: 10.1016/S0140-6736(13)60595-4. Epub 2013 May 31.

Sustained high levels of neuregulin-1 in the longest-lived rodents; a key determinant of rodent longevity.

Aging Cell. 2012 Apr;11(2):213-22. doi: 10.1111/j.1474-9726.2011.00772.x. Epub 2011 Dec 29.

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