Ribarić Elizabeta, Velić Ismar, Bobinac Ana
Faculty of Economics and Business, Center for Health Economics and Pharmacoeconomics, University of Rijeka, Ivana Filipovića 4, 51000, Rijeka, Croatia.
Appl Health Econ Health Policy. 2024 Jan;22(1):97-106. doi: 10.1007/s40258-023-00829-1. Epub 2023 Oct 4.
We explored the monetary value of the end-of-life (EoL) health gains, that is, the value of a life-year (VOLY) gained at the end of a patient's life in Croatia. We tested whether the nature of the illness under valuation (cancer and/or rare disease) is a factor in the valuation of EoL-VOLYs. The aim was for our results to contribute to the health and longevity valuation literature and more particularly to the debate on the appropriate cost-effectiveness threshold for EoL treatments as well as to provide input into the debate on the justifiability of a cancer and/or a rare disease premium when evaluating therapies.
A contingent valuation was conducted in an online survey using a representative sample of the Croatian population (n = 1500) to calculate the willingness to pay for gains in the remaining life expectancy at the EoL, from the social-inclusive-individual perspective, using payment scales and an open-ended payment vehicle. Our approach mimics the actual decision-making problem of deciding whether to reimburse therapies targeting EoL conditions such as metastatic cancer whose main purpose is to extend life (and not add quality to life).
Average EoL-VOLY across all scenarios was estimated at €67,000 (median €40,000). In scenarios that offered respondents 1 full year of life extension, EoL-VOLY was estimated at €33,000 (median €22,000). Our results show that the type of illness is irrelevant for EoL-VOLY evaluations.
The pressure to reimburse expensive therapies targeting EoL conditions will continue to increase. Delivering "value for money" in healthcare, both in countries with relatively higher and lower budget restrictions, requires the valuation of different types of health gains, which should, in turn, affect our ability to evaluate their cost effectiveness.
我们探讨了临终(EoL)健康收益的货币价值,即克罗地亚患者生命末期获得的生命年价值(VOLY)。我们测试了所评估疾病的性质(癌症和/或罕见病)是否是临终VOLY估值的一个因素。目的是使我们的结果有助于健康和寿命估值文献,更具体地说,有助于关于临终治疗适当成本效益阈值的辩论,并为评估治疗时癌症和/或罕见病溢价的合理性辩论提供参考。
通过在线调查对克罗地亚具有代表性的人群样本(n = 1500)进行了意愿评估,从社会包容个体的角度,使用支付量表和开放式支付方式,计算为临终时剩余预期寿命的增加支付的意愿。我们的方法模拟了决定是否报销针对临终状况(如转移性癌症,其主要目的是延长生命而非提高生活质量)的治疗的实际决策问题。
所有情景下的平均临终VOLY估计为67,000欧元(中位数为40,000欧元)。在为受访者提供1整年生命延长的情景中,临终VOLY估计为33,000欧元(中位数为22,000欧元)。我们的结果表明,疾病类型与临终VOLY评估无关。
报销针对临终状况的昂贵治疗的压力将持续增加。在预算限制相对较高和较低的国家,在医疗保健中实现“物有所值”需要对不同类型的健康收益进行估值,这反过来又会影响我们评估其成本效益的能力。