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首发精神病患者中欺凌与症状表现的关系。

The relationship between bullying and symptom presentation in first-episode psychosis.

机构信息

The Athens First Episode Psychosis Research Study Group. 1st Department of Psychiatry, National and Kapodistrian University of Athens Medical School, Eginition Hospital, Athens.

出版信息

Psychiatriki. 2024 Mar 28;35(1):17-25. doi: 10.22365/jpsych.2023.021. Epub 2023 Sep 29.

Abstract

Multiple recent studies have indicated that adverse psycho-traumatic experiences are particularly significant, if not the most significant, among the environmental factors that participate in the aetiology of schizophrenic spectrum disorders. The prevalence of bullying in the adolescent population has increased dramatically compared to earlier reports. This may be related to the recent development of communication technology and the use of social media, which have expanded the means by which bullying can be practiced. The present study aims to investigate the association between bullying victimisation and psychotic symptoms in First-Episode Psychosis (FEP) patients, hypothesising that patients who have a bullying history may have increased psychotic symptoms and a more unfavourable early trajectory after treatment as usual compared to patients who do not have a bullying history. Research data were collected from a sample of men and women of the Greek general population aged between 16 and 45 (N=225) who experienced a FEP in the context of the Athens First-Episode Psychosis (FEP) Study. The assessment of bullying was performed using the Retrospective Bullying Questionnaire (RBQ). Assessment of positive and negative psychotic symptoms and general psychopathology was performed using the corresponding subscales of the Positive and Negative Syndrome Scale (PANSS) at baseline and after 4 weeks of treatment as usual. Clinical remission was assessed based on the baseline and follow-up values of the PANSS and on Andreasen's symptomatic criteria. Methodologically, Pearson's chi-square test was used to compare the history of bullying between men and women, while linear and logistic regression models were used to check the correlations between history of bullying and symptom severity at baseline and 4-week follow-up, as well as the correlation between history of bullying and remission. The prevalence of bullying history in our sample of patients (N:225) with a FEP was 51.4% (114/225). Bullying was recorded in our study participants with equal frequency in women and men. According to the analysis results, the patients who had experienced bullying did not present at baseline with significantly increased psychotic symptoms compared to the patients who did not have a history of bullying. In addition, bullying was not associated with reduced remission according to Andreasen's criteria. However, the patients who had experienced bullying were found to have significantly increased negative symptoms (B=1.66; SE=0.70; p=0.018) and increased PANSS total score (B=4.81; SE=2.34; p=0.041) at 4-week follow-up. Our results highlight the persistence of negative and overall symptoms as an impact of bullying on the development of the FEP and align with studies that support the consideration of a history of bullying during both the diagnostic and therapeutic processes.

摘要

多项近期研究表明,在参与精神分裂谱系障碍发病的环境因素中,不良心理创伤经历尤为重要,如果不是最重要的话。与早期报告相比,青少年群体中欺凌现象的发生率显著增加。这可能与最近通讯技术的发展和社交媒体的使用有关,这些技术扩大了欺凌行为的实施手段。本研究旨在调查欺凌受害与首发精神病(FEP)患者精神病症状之间的关联,假设与没有欺凌史的患者相比,有欺凌史的患者在接受常规治疗后可能会出现更多的精神病症状和更不利的早期病程。研究数据来自于年龄在 16 至 45 岁之间的希腊一般人群中的男性和女性样本(N=225),他们在雅典首发精神病(FEP)研究中经历了 FEP。欺凌的评估是使用回溯性欺凌问卷(RBQ)进行的。阳性和阴性精神病症状以及一般精神病症状的评估是使用阳性和阴性综合征量表(PANSS)的相应分量表在基线和常规治疗 4 周后进行的。根据 PANSS 的基线和随访值以及 Andreasen 的症状标准,评估临床缓解情况。方法上,使用 Pearson's chi-square 检验比较男性和女性之间的欺凌史,同时使用线性和逻辑回归模型检查欺凌史与基线和 4 周随访时症状严重程度之间的相关性,以及欺凌史与缓解之间的相关性。在我们的首发精神病患者样本(N:225)中,有欺凌史的患者的患病率为 51.4%(114/225)。在我们的研究参与者中,女性和男性的欺凌发生率相等。根据分析结果,与没有欺凌史的患者相比,经历过欺凌的患者在基线时并没有表现出明显增加的精神病症状。此外,根据 Andreasen 的标准,欺凌与缓解率降低无关。然而,研究发现,经历过欺凌的患者在 4 周随访时出现明显增加的阴性症状(B=1.66;SE=0.70;p=0.018)和 PANSS 总分增加(B=4.81;SE=2.34;p=0.041)。我们的结果强调了欺凌对首发精神病发展的负面影响,表现为阴性和整体症状的持续存在,这与支持在诊断和治疗过程中考虑欺凌史的研究结果一致。

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