Department of Cardiothoracic Surgery, Affiliated Hospital of Putian University, Putian, 351100, Fujian, China.
J Cardiothorac Surg. 2023 Oct 4;18(1):268. doi: 10.1186/s13019-023-02370-7.
This study aims to investigate the outcomes of patients who received early fiberoptic bronchoscopic sputum aspiration and lavage after thoracoscopic and laparoscopic esophagectomy due to esophageal cancer.
A prospective randomized clinical trial was performed between March 2020 and June 2022. Patients who were scheduled for thoracoscopic and laparoscopic esophagectomy due to esophageal cancer were enrolled. Then, these patients were assigned to the control group (traditional postoperative care) and study group (traditional postoperative care with early bronchoscopic sputum aspiration and lavage). The outcomes, which included the length of hospital stay and medical expenses, and postoperative complications, which included pulmonary infection, atelectasis, respiratory dysfunction and anastomotic leakage, were compared between these two groups.
A total of 106 patients were enrolled for the present study, and 53 patients were assigned for the control and study groups. There were no statistically significant differences in gender, age, and location of the esophageal cancer between the two groups. Furthermore, the length of hospital stay was statistically significantly shorter and the medical expenses were lower during hospitalization in the study group, when compared to the control group (12.3 ± 1.2 vs. 18.8 ± 1.3 days, 5.5 ± 0.9 vs. 7.2 ± 1.2 Chinese Yuan, respectively; all, P < 0.05). Moreover, there were statistically significantly fewer incidences of overall complications in study group, when compared to the control group (20.7% vs.45.2%, P < 0.05).
For patients with esophageal cancer, early fiberoptic bronchoscopic sputum aspiration and lavage after thoracoscopic and laparoscopic esophagectomy can shorten the length of hospital stay, and lower the medical expense and incidence of postoperative complications.
本研究旨在探讨接受胸腔镜和腹腔镜食管癌手术后早期纤维支气管镜吸痰灌洗的患者的结局。
这是一项在 2020 年 3 月至 2022 年 6 月间进行的前瞻性随机临床试验。纳入因食管癌而行胸腔镜和腹腔镜食管癌切除术的患者。然后，这些患者被分配到对照组（传统术后护理）和研究组（传统术后护理加早期支气管镜吸痰灌洗）。比较两组患者的住院时间和医疗费用等结局，以及肺部感染、肺不张、呼吸功能障碍和吻合口漏等术后并发症。
本研究共纳入 106 例患者，其中 53 例患者被分配至对照组和研究组。两组患者的性别、年龄和食管癌部位无统计学差异。此外，与对照组相比，研究组的住院时间更短，住院期间的医疗费用更低（12.3±1.2 天比 18.8±1.3 天，5.5±0.9 元比 7.2±1.2 元，均 P<0.05）。此外，研究组的总并发症发生率明显低于对照组（20.7%比 45.2%，P<0.05）。
对于食管癌患者，胸腔镜和腹腔镜食管癌手术后早期纤维支气管镜吸痰灌洗可以缩短住院时间，降低医疗费用，减少术后并发症的发生。
