Leas Derek A, Schultz Daniel C, Huigens Robert W
Department of Medicinal Chemistry, Center for Natural Products Drug Discovery and Development (CNPD3), College of Pharmacy, University of Florida, 1345 Center Drive, Gainesville, FL 32610, USA.
SynOpen. 2023 Jun;7(2):165-185. doi: 10.1055/a-2048-8412. Epub 2023 May 11.
This graphical review provides a concise overview of indole alkaloids and chemical reactions that have been reported to transform both these natural products and derivatives to rapidly access new molecular scaffolds. Select biologically active compounds from these synthetic efforts are reported herein.
本图形综述简要概述了吲哚生物碱以及据报道可将这些天然产物及其衍生物进行转化以快速获得新分子骨架的化学反应。本文报道了这些合成研究中具有生物活性的化合物。