PtrA regulates prodigiosin synthesis and biological functions in FZSF02.

is a gram-negative bacterium that is able to produce many secondary metabolites, such as the prominent red pigment prodigiosin (PG). In this work, a -disrupted mutant strain with reduced PG production was selected from Tn transposon mutants. RT-qPCR results indicated that promoted elevated transcription of the gene cluster in FZSF02. Furthermore, we found that also controls several other important biological functions of , including swimming and swarming motilities, biofilm formation, hemolytic activity, and stress tolerance. In conclusion, this study demonstrates that is a PG synthesis-promoting factor in and provides a brief understanding of the regulatory mechanism of in cell motility and hemolytic activity.