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口腔内放置支架的患者在头颈部放疗前后的张口度评估。

Assessment of mouth opening before and after head and neck radiotherapy in patients with intraoral stents.

作者信息

Carneiro Mailon Cury, Chicrala Gabriela Moura, Freitas Vitor Mota, de Lima Toyoshima Guilherme Hideki, Santos Paulo Sérgio da Silva

机构信息

Department of Surgery, Stomatology, Pathology, and Radiology; Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.

Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.

出版信息

Rep Pract Oncol Radiother. 2023 Jul 25;28(3):352-360. doi: 10.5603/RPOR.a2023.0039. eCollection 2023.

Abstract

BACKGROUND

We evaluated the evolution of mouth opening before and after radiotherapy of the head and neck in patients using intraoral stents.

MATERIALS AND METHODS

Twenty-one patients with head and neck cancer who were indicated for radiotherapy participated in this study. Maximum interincisal opening measurements were performed before and after radiotherapy. Paired analyses of the pre- and post-radiotherapy groups were performed using paired samples t-tests and correlation analyses using Spearman's correlation test, with p < 0.05 considered statistically significant.

RESULTS

Paired analyses of the pre- and post-radiotherapy groups revealed a statistically significant reduction in post-radiotherapy maximum interincisal opening (p < 0.001). However, only four individuals were diagnosed with trismus after radiotherapy. Regarding the correlation tests, no statistically significant differences were observed between the differences in pre- and post-radiotherapy maximum interincisal opening values and the study variables.

CONCLUSION

The use of prosthetic devices during head and neck radiotherapy can reduce radiation doses in areas of no interest, thereby preventing the acute and late toxicities associated with cancer therapy.

摘要

背景

我们评估了使用口腔内支架的患者在头颈部放疗前后张口度的变化情况。

材料与方法

21名头颈部癌症患者参与了本研究,这些患者均需接受放疗。在放疗前后分别测量最大切牙间开口度。对放疗前后两组数据进行配对分析,采用配对样本t检验,并用Spearman相关检验进行相关性分析,p < 0.05被认为具有统计学意义。

结果

放疗前后两组的配对分析显示,放疗后最大切牙间开口度有统计学意义的降低(p < 0.001)。然而,放疗后仅4人被诊断为牙关紧闭。关于相关性检验,放疗前后最大切牙间开口度值的差异与研究变量之间未观察到统计学显著差异。

结论

在头颈部放疗期间使用修复装置可减少非靶区的辐射剂量,从而预防与癌症治疗相关的急慢性毒性反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b7d/10547412/f202db9dc5ac/rpor-28-3-352f1.jpg

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