Unit of Urology, Department of Woman, Child and General and Specialized Surgery, Luigi Vanvitelli University of Campania, Naples, Italy -
Department of Urology, Rush University Medical Center, Chicago, IL, USA -
Minerva Urol Nephrol. 2024 Apr;76(2):166-175. doi: 10.23736/S2724-6051.23.05466-6. Epub 2023 Oct 5.
Quality of Life and Sexuality with Penile Prosthesis (QoLSPP) is the first validated questionnaire to specifically evaluate the satisfaction of patients undergoing penile prosthesis implantation. Our primary aim was to conduct a systematic review and pooled analysis of articles reporting QoLSPP.
A comprehensive bibliographic search on the MEDLINE, Scopus, Web of Science, and Cochrane Library databases was performed in April 2023. Studies were selected if they assessed male subjects (P) undergoing penile prosthesis implantation (I) with or without comparison with other treatments (C), reporting the patient satisfaction according to QoLSPP (O). Prospective and retrospective original studies were included (S). The risk of bias was assessed using the ROBINS-I tool and the Knoll method. Means and standard deviations (SDs) of QoLSPP scores were included in the pooled analysis. PROSPERO ID: "CRD42023427261."
A total of 10 studies investigating 1105 patients were included in the systematic review; of these, eight articles describing the outcomes of 693 subjects were eligible for the pooled analysis. Overall serious risk of bias was found in 2/3 of nonrandomized comparative studies (66%), while seven single-arm studies (100%) were classified as having a high risk of bias. Pooled analysis of the QoLSPP-Functional domain revealed an overall effect size (ES) of 4.22 points (95% CI 4.04-4.40; P<0.001). The QoLSPP-Relational pooled score was 4.17 points (95% CI 4.03-4.31; P<0.001). The QoLSPP-Social pooled score corresponded to 4.21 points (95% CI 4.02-4.40; P<0.001). Pooled analysis of the QoLSPP-Personal domain showed an overall ES of 3.97 points (95% CI 3.61-4.32; P<0.001). There was insufficient data to pool QoLSPP total scores.
Patients undergoing penile prosthesis implantation report positive scores in all QoLSPP domains, demonstrating high satisfaction levels. Future studies are needed to improve the evidence on the topic.
生活质量和性满意度与阴茎假体（QoLSPP）是第一个专门评估接受阴茎假体植入患者满意度的经过验证的问卷。我们的主要目的是对报告 QoLSPP 的文章进行系统评价和汇总分析。
2023 年 4 月，我们对 MEDLINE、Scopus、Web of Science 和 Cochrane Library 数据库进行了全面的文献检索。如果研究评估了接受阴茎假体植入（I）的男性受试者（P），无论是否与其他治疗（C）进行比较，并根据 QoLSPP（O）报告患者满意度，则将其纳入研究。包括前瞻性和回顾性原始研究（S）。使用 ROBINS-I 工具和 Knoll 方法评估偏倚风险。汇总分析中包括 QoLSPP 评分的均值和标准差（SD）。PROSPERO ID：“CRD42023427261”。
系统评价共纳入 10 项研究，涉及 1105 例患者；其中，8 篇文章描述了 693 例受试者的结果，符合汇总分析的纳入标准。3 项非随机对照研究（66%）总体偏倚风险为严重，而 7 项单臂研究（100%）被归类为高偏倚风险。QoLSPP-功能域的汇总分析显示，总体效应大小（ES）为 4.22 分（95%CI 4.04-4.40；P<0.001）。QoLSPP-关系的汇总评分是 4.17 分（95%CI 4.03-4.31；P<0.001）。QoLSPP-社会的汇总评分相当于 4.21 分（95%CI 4.02-4.40；P<0.001）。QoLSPP-个人域的汇总分析显示，总体 ES 为 3.97 分（95%CI 3.61-4.32；P<0.001）。没有足够的数据汇总 QoLSPP 总分。
接受阴茎假体植入的患者在 QoLSPP 的所有领域都报告了积极的评分，表明他们的满意度很高。需要进一步的研究来提高关于该主题的证据水平。
