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区分高自闭症风险幼儿的早期感觉特征,以及与后期临床结局和诊断的关联。

Differentiating early sensory profiles in toddlers at elevated likelihood of autism and association with later clinical outcome and diagnosis.

机构信息

Scientific Institute, IRCCS E. Medea, Bosisio Parini, Lecco, Italy.

出版信息

Autism. 2024 Jul;28(7):1654-1666. doi: 10.1177/13623613231200081. Epub 2023 Oct 5.

Abstract

Early sensory responsiveness may produce cascading effects on later development, but the relation between sensory profiles and autistic diagnosis remains unclear. In a longitudinal sample of toddlers at elevated likelihood for autism, we aimed to characterize sensory subgroups and their association with clinical outcomes later on. Three sensory subgroups were described and early sensory sensitivity plays a significant role in later development and diagnosis. This study supported the importance of examining different levels of sensory patterns to dissect the phenotypic heterogeneity in sensory processing. As sensory differences are associated with later developmental outcomes, these results may be critical when designing intervention needs and support for children at increased likelihood for neurodevelopmental disorders.

摘要

早期感觉反应可能对后期发展产生级联效应,但感觉特征与自闭症诊断之间的关系尚不清楚。在一个自闭症风险较高的纵向幼儿样本中,我们旨在描述感觉亚组及其与以后临床结果的关系。描述了三个感觉亚组,早期感觉敏感性在后期发展和诊断中起着重要作用。这项研究支持了检查不同水平的感觉模式以剖析感觉处理表型异质性的重要性。由于感觉差异与后期发育结果有关,因此当为神经发育障碍风险增加的儿童设计干预需求和支持时,这些结果可能至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9881/11191663/93163aba65b0/10.1177_13623613231200081-fig1.jpg

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