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自闭症高家族患病风险幼儿的感觉特征与后期适应功能的关系

Sensory Profiles in Relation to Later Adaptive Functioning Among Toddlers at High-Familial Likelihood for Autism.

作者信息

Worthley Emma, Grzadzinski Rebecca, Zwaigenbaum Lonnie, Dager Stephen R, Estes Annette M, Hazlett Heather C, Schultz Robert T, Piven Joseph, Wolff Jason J

机构信息

University of Minnesota, 56 East River Road, 55455, Minneapolis, MN, USA.

University of North Carolina at Chapel Hill, 321 S Columbia St, 27516, Chapel Hill, NC, USA.

出版信息

J Autism Dev Disord. 2024 Jun;54(6):2183-2197. doi: 10.1007/s10803-022-05869-5. Epub 2023 Apr 5.

Abstract

This study investigated the extent to which sensory responsivity in infancy contributes to adaptive behavior development among toddlers at high-familial likelihood for autism. Prospective, longitudinal data were analyzed for 218 children, 58 of whom received an autism diagnosis. Results indicated that sensory profiles at age one year (hyperresponsivity, sensory seeking) were negatively associated with later adaptive behavior, particularly for socialization, at age 3 years regardless of diagnostic status. These results suggest that early differences in sensory responsivity may have downstream developmental consequences related to social development among young children with high-familial likelihood for autism.

摘要

本研究调查了婴儿期的感觉反应性在多大程度上有助于高自闭症家族患病可能性的幼儿的适应性行为发展。对218名儿童的前瞻性纵向数据进行了分析,其中58名儿童被诊断为自闭症。结果表明,一岁时的感觉特征(反应过度、感觉寻求)与三岁时后期的适应性行为呈负相关,尤其是在社交方面,无论诊断状况如何。这些结果表明,感觉反应性的早期差异可能对高自闭症家族患病可能性的幼儿的社交发展产生与发育相关的下游后果。

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