From the Departments of Radiology and Nuclear Medicine.
Hand and Plastic Surgery, Cantonal Hospital Lucerne, Lucerne.
Clin Nucl Med. 2023 Dec 1;48(12):1047-1048. doi: 10.1097/RLU.0000000000004823. Epub 2023 Sep 21.
Tenosynovial giant cell tumor, previously known as pigmented villonodular synovitis, is a benign low-grade fibrohistiocytic proliferation with hemosiderin deposits in synovial joints. Mostly affecting the knee, it can also manifest in other synovial joints, infrequently also in the wrist. Tenosynovial giant cell tumor typically causes intense radionuclide uptake in all phases in planar bone scintigraphy, making a differentiation from other bone tumors or osteomyelitis difficult, especially in cases associated with extensive bone destruction. We present a case of an unusually advanced and extended tenosynovial giant cell tumor of the wrist in bone scintigraphy, SPECT/CT, radiograph, and MRI.
腱鞘巨细胞瘤,以前称为色素绒毛结节性滑膜炎,是一种良性低度纤维组织细胞增生,伴有滑膜关节内的含铁血黄素沉积。主要影响膝关节,也可在其他滑膜关节表现,偶尔也在腕关节表现。腱鞘巨细胞瘤通常在平面骨闪烁显像的所有阶段都引起强烈的放射性核素摄取,使其难以与其他骨肿瘤或骨髓炎区分,尤其是在伴有广泛骨破坏的情况下。我们报告了一例腕部腱鞘巨细胞瘤在骨闪烁显像、SPECT/CT、X 线摄影和 MRI 上表现出异常的晚期和广泛病变的病例。