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先天性颅内肿瘤

Congenital intracranial neoplasms.

作者信息

Ellams I D, Neuhäuser G, Agnoli A L

出版信息

Childs Nerv Syst. 1986;2(4):165-8. doi: 10.1007/BF00706804.

Abstract

The clinical and histological findings are described in 12 infants (5 boys, 7 girls) suffering from congenital intracranial tumors. An enlarged head or signs of increased intracranial pressure were present at birth or within the first 12 months of life (average 5.1 months). The histological picture of the tumors (6 supratentorial, 6 infratentorial) varied. In 6 children a ventriculoperitoneal shunt was necessary; partial or total removal of the tumor was attempted in 5 infants; 4 patients received irradiation. Prognosis was poor, and survival time averaged 13 months. A short review of the literature is given; new diagnostic techniques (computed tomography, magnetic resonance imaging) allow earlier diagnosis. However, because of the size and location, successful treatment is rarely possible.

摘要

本文描述了12例患有先天性颅内肿瘤的婴儿(5名男孩,7名女孩)的临床和组织学表现。出生时或出生后12个月内(平均5.1个月)出现头部增大或颅内压升高的迹象。肿瘤的组织学表现各异(幕上6例,幕下6例)。6名儿童需要进行脑室腹腔分流术;5名婴儿尝试部分或全部切除肿瘤;4名患者接受了放疗。预后较差,平均生存时间为13个月。本文对相关文献进行了简要综述;新的诊断技术(计算机断层扫描、磁共振成像)有助于早期诊断。然而,由于肿瘤的大小和位置,很少能够成功治疗。

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