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手术治疗的Pilon骨折的结果:糖尿病患者与非糖尿病患者的比较

Outcomes of Surgically Treated Pilon Fractures: A Comparison of Patients With and Without Diabetes.

作者信息

Chowdary Ashish R, Ravi Varun, Wukich Dane K, Sambandam Senthil

机构信息

University of Texas Southwestern Medical Center, Dallas, TX.

Department of Orthopaedic Surgery, University of Texas Southwestern Medical Center, Dallas, TX.

出版信息

J Orthop Trauma. 2023 Dec 1;37(12):650-657. doi: 10.1097/BOT.0000000000002701.

Abstract

OBJECTIVE

To compare systemic complications, fracture healing-related complications, and reoperation rates for pilon fractures in patients with and without diabetes.

DESIGN

Retrospective cohort study.

SETTING

National administrative claims database with patient records.

PATIENTS

Patients from the years 2016 to 2020 with surgically treated closed or open pilon fractures were included.

INTERVENTION

Patients with either closed or open pilon fractures with diabetes were compared with those without diabetes. Subgroup analysis was performed on diabetic patients with and without neuropathy.

OUTCOMES

Postoperative systemic complications at 90 days, fracture healing complications at 90 days and 1 year, and reoperative rates at 90 days and 1 year.

RESULTS

Two thousand six hundred fifty-four (31.4%) patients with closed fractures and 491 (28.7%) patients with open fractures had a diagnosis of diabetes. In both open and closed fractures, we identified significantly higher rates of acute kidney injury, cardiac arrest, and surgical site infection in diabetic patients compared with nondiabetic patients. In addition, we found significantly higher rates of below knee amputations in diabetic patients. Diabetic patients with closed fractures had significantly higher rates of wound healing-related reoperations. Patients with advanced diabetic disease, as suggested by the presence of neuropathy, had higher rates of nonunion and post-traumatic arthritis.

CONCLUSIONS

The data presented here provide updated estimates on complication rates in pilon fractures using a large sample size. In addition, our work identifies differences in outcomes for patients with and without diabetes after pilon fracture surgery. Our data suggest that patients with severe diabetes are prone to higher rates of healing complications and may benefit from additional therapeutic support.

LEVEL OF EVIDENCE

Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.

摘要

目的

比较糖尿病患者和非糖尿病患者胫腓骨远端骨折的全身并发症、骨折愈合相关并发症及再次手术率。

设计

回顾性队列研究。

地点

拥有患者记录的国家行政索赔数据库。

患者

纳入2016年至2020年接受手术治疗的闭合性或开放性胫腓骨远端骨折患者。

干预措施

将患有糖尿病的闭合性或开放性胫腓骨远端骨折患者与无糖尿病患者进行比较。对有和无神经病变的糖尿病患者进行亚组分析。

结果

2654例(31.4%)闭合性骨折患者和491例(28.7%)开放性骨折患者被诊断患有糖尿病。在开放性和闭合性骨折中,我们发现糖尿病患者急性肾损伤、心脏骤停和手术部位感染的发生率显著高于非糖尿病患者。此外,我们发现糖尿病患者膝下截肢率显著更高。闭合性骨折的糖尿病患者伤口愈合相关再次手术率显著更高。有神经病变提示的晚期糖尿病患者骨不连和创伤后关节炎发生率更高。

结论

本文提供了使用大样本量对胫腓骨远端骨折并发症发生率的最新估计。此外,我们的研究确定了胫腓骨远端骨折手术后糖尿病患者和非糖尿病患者的预后差异。我们的数据表明,严重糖尿病患者愈合并发症发生率较高,可能受益于额外的治疗支持。

证据水平

预后III级。有关证据水平的完整描述,请参阅作者指南。

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