Department of Clinical Nutrition and Food Services, Nihonkai Sakata Rehabilitation Hospital, Sakata City, Yamagata, Japan.
Department of Center for Sarcopenia and Malnutrition Research, Kumamoto Rehabilitation Hospital, Kikuchi County, Kumamoto, Japan.
J Stroke Cerebrovasc Dis. 2023 Dec;32(12):107345. doi: 10.1016/j.jstrokecerebrovasdis.2023.107345. Epub 2023 Oct 3.
The usefulness of malnutrition diagnosed using the Global Leadership Initiative on Malnutrition (GLIM) criteria as a predictor of recovery of activities of daily living is unclear. This study aimed to investigate whether baseline malnutrition diagnosed using the GLIM criteria was predictive of recovery of activities of daily living in older patients with post-acute stroke.
A retrospective cohort study was conducted in patients aged ≥70 years with post-acute stroke. The outcome was activities of daily living measured using the motor domain of the Functional Independence Measure (FIM-motor) score at discharge. Participants were classified as malnourished or non-malnourished according to the GLIM criteria. Multivariate linear regression analyses were performed to determine whether baseline malnutrition diagnosed using the GLIM criteria was predictive of the FIM-motor score at discharge. The analysis was adjusted for clinically relevant covariates associated with rehabilitation outcomes after stroke.
A total of 236 patients (mean age, 80.0 years; female, 54.2%) were included in the analysis. On admission, 83 (35.2%) patients were diagnosed with malnutrition. Multivariate linear regression analyses showed that malnutrition diagnosed using the GLIM criteria was predictive of the FIM-motor score at discharge (β = -0.347, P < 0.001).
Identifying malnutrition using the GLIM criteria is useful for predicting recovery of activities of daily living in older patients with post-acute stroke.
使用全球营养不良倡议（GLIM）标准诊断的营养不良对急性后脑卒中老年患者日常生活活动恢复的预测作用尚不清楚。本研究旨在探讨急性后脑卒中老年患者使用 GLIM 标准诊断的基线期营养不良是否可以预测日常生活活动的恢复。
这是一项对年龄≥70 岁的急性后脑卒中患者进行的回顾性队列研究。结局指标为使用功能独立性测量（FIM）运动域评分（FIM-motor）评估的日常生活活动。根据 GLIM 标准将参与者分为营养不良或非营养不良。使用多元线性回归分析确定使用 GLIM 标准诊断的基线期营养不良是否可以预测出院时的 FIM-motor 评分。分析调整了与脑卒中后康复结局相关的临床相关协变量。
共纳入 236 例患者（平均年龄 80.0 岁，女性 54.2%）进行分析。入院时，83 例（35.2%）患者被诊断为营养不良。多元线性回归分析显示，使用 GLIM 标准诊断的营养不良与出院时的 FIM-motor 评分相关（β=-0.347，P<0.001）。
使用 GLIM 标准识别营养不良对预测急性后脑卒中老年患者日常生活活动的恢复具有重要意义。
