内源性大麻素调制由皮质-杏仁核投射控制的恐惧消退。

Endocannabinoids modulate fear extinction controlled by a cortical-amygdala projection.

机构信息

Department of Psychology, University of California, Los Angeles, CA 90095, USA.

出版信息

Neuron. 2023 Oct 4;111(19):2948-2950. doi: 10.1016/j.neuron.2023.09.011.

DOI:10.1016/j.neuron.2023.09.011

Abstract

The projection from the medial prefrontal cortex to the amygdala is a key node in fear extinction. In this issue of Neuron, Gunduz-Cinar et al. show that extinction induction by this projection requires recruitment of endocannabinoids (eCBs) in the amygdala.

摘要

从内侧前额叶皮层到杏仁核的投射是恐惧消退的关键节点。在本期神经元杂志上，Gunduz-Cinar 等人表明，该投射诱导的消退需要杏仁核内内源性大麻素 (eCBs) 的募集。