Meningococcal Reference Unit, UK Health Security Agency, Manchester M13 9WL, United Kingdom.
Meningococcal Reference Unit, UK Health Security Agency, Manchester M13 9WL, United Kingdom.
J Infect. 2023 Dec;87(6):479-489. doi: 10.1016/j.jinf.2023.09.007. Epub 2023 Oct 4.
Few data outside of individual case reports are available on non-meningococcal, non-gonococcal species of Neisseria as causative agents of invasive disease. This review collates disease, organism and patient information from case reports on the topic.
A literature search was performed examining articles describing diseases caused by non-meningococcal and non-gonococcal Neisseria.
Neisseria present as opportunistic pathogens causing a wide variety of diseases including serious presentations, endocarditis being the most common condition described and N. mucosa the most commonly presenting pathogen overall. Disease may occur in otherwise healthy patients, although risk factors for infection include recent surgery, an immunocompromised state, poor oral health, and intravenous drug use.
Commensal Neisseria infections are rare but can present serious invasive diseases. Further research is required to determine why some species cause disease more than others or why some are inclined towards particular manifestations.
关于奈瑟菌属中非脑膜炎奈瑟菌和非淋病奈瑟菌作为侵袭性疾病病原体的病例报告以外的数据很少。本综述从关于该主题的病例报告中汇集了疾病、病原体和患者信息。
进行了文献检索，检查了描述由非脑膜炎奈瑟菌和非淋病奈瑟菌引起的疾病的文章。
奈瑟菌属是机会性病原体，可引起多种疾病，包括严重的表现，其中心内膜炎是最常见的描述的疾病，黏膜奈瑟菌是最常见的总体病原体。疾病可能发生在其他健康的患者中，尽管感染的危险因素包括最近的手术、免疫功能低下、口腔健康状况不佳和静脉内药物使用。
共生奈瑟菌感染很少见，但可引起严重的侵袭性疾病。需要进一步研究以确定为什么某些物种比其他物种更容易引起疾病，或者为什么某些物种倾向于特定的表现。
