Department of Pharmacy, Emergency Medicine, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.
Clin Geriatr Med. 2023 Nov;39(4):635-645. doi: 10.1016/j.cger.2023.04.008. Epub 2023 May 11.
Older adults are given therapies to enhance the quality and longevity of life, but with the benefits of medication therapy also comes the potential for adverse drug events (ADEs). Avoiding ADEs has become a national health priority with substantial impact on health outcomes and health care costs. The presence of multimorbidity, changes in physiologic function, and polypharmacy make older adults more vulnerable to medication-related ADEs. Use of interactive support tools in the form of geriatric-friendly medication order sets and geriatric consultations along with pharmacist-led medication review and optimization are imperative to decrease the occurrence of ADEs and unnecessary prescribing cascades.
老年人接受治疗以提高生活质量和延长寿命，但药物治疗的益处也带来了潜在的药物不良事件 (ADE)。避免 ADE 已成为国家卫生重点，对健康结果和医疗保健成本有重大影响。多种疾病的存在、生理功能的变化和多种药物的使用使老年人更容易受到与药物相关的 ADE 的影响。使用以老年友好型药物医嘱集和老年咨询形式的交互式支持工具，以及由药剂师主导的药物审查和优化，对于减少 ADE 和不必要的处方级联反应至关重要。
