McStay B, Reeder R H
Cell. 1986 Dec 26;47(6):913-20. doi: 10.1016/0092-8674(86)90806-8.
On the Xenopus laevis ribosomal genes, RNA polymerase traverses the entire repeating unit of gene plus spacer and terminates just upstream of the next gene promoter. A conserved 7 bp element located at about -200 is an essential part of this terminator. In this paper we show that, in addition to its termination function, this same sequence motif acts as an upstream element of the adjacent promoter and appears to contribute to the long-term stability of the transcription complex.
在非洲爪蟾的核糖体基因上，RNA聚合酶穿过基因加间隔区的整个重复单元，并在下一个基因启动子上游终止。位于约-200处的一个保守的7碱基对元件是该终止子的重要组成部分。在本文中，我们表明，除了其终止功能外，这个相同的序列基序还作为相邻启动子的上游元件，并且似乎有助于转录复合物的长期稳定性。
