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利用护理初诊时的CD4细胞计数监测2017年至2020年大圣路易斯地区人类免疫缺陷病毒预防、治疗及公共卫生项目的成效

Leveraging CD4 Cell Count at Entry Into Care to Monitor Success of Human Immunodeficiency Virus Prevention, Treatment, and Public Health Programming in the Greater St Louis Area Between 2017 and 2020.

作者信息

Filiatreau Lindsey M, Mody Aaloke, Vo Daniel, Bradley Cory, Ramakrishnan Aditi, López Julia, O'Halloran Jane, Trolard Anne, Powderly William G, Geng Elvin H

机构信息

Division of Infectious Diseases, School of Medicine, Washington University, St Louis, Missouri, USA.

出版信息

Open Forum Infect Dis. 2023 Sep 18;10(10):ofad477. doi: 10.1093/ofid/ofad477. eCollection 2023 Oct.

DOI:10.1093/ofid/ofad477
PMID:37799129
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10549207/
Abstract

CD4 cell count at entry into human immunodeficiency virus (HIV) care is a useful indicator of success of multiple steps in HIV public health programming. We demonstrate that CD4 cell count at care initiation was stable in St Louis between 2017 and 2019 but declined in 2020. Missouri efforts in the Ending the HIV Epidemic plan should focus on rapidly identifying individuals with undiagnosed HIV infection.

摘要

进入人类免疫缺陷病毒(HIV)治疗时的CD4细胞计数是HIV公共卫生规划中多个步骤成功与否的一个有用指标。我们证明,2017年至2019年期间,圣路易斯市开始治疗时的CD4细胞计数保持稳定,但在2020年有所下降。密苏里州在《终结HIV流行计划》中的努力应集中于迅速识别未被诊断出感染HIV的个体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f70/10549207/7f3970182d35/ofad477f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f70/10549207/7f3970182d35/ofad477f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f70/10549207/7f3970182d35/ofad477f1.jpg

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本文引用的文献

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HIV Testing Before and During the COVID-19 Pandemic - United States, 2019-2020.HIV 检测在新冠大流行之前和期间 - 美国,2019-2020。
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2005-2018 年美国人类免疫缺陷病毒感染者进入护理时和开始抗逆转录病毒治疗时的 CD4 计数。
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Clin Infect Dis. 2018 Mar 5;66(6):893-903. doi: 10.1093/cid/cix915.
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Impact of Age and Sex on CD4+ Cell Count Trajectories following Treatment Initiation: An Analysis of the Tanzanian HIV Treatment Database.治疗开始后年龄和性别对CD4+细胞计数轨迹的影响:坦桑尼亚艾滋病毒治疗数据库分析
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