Debaene Britt, Vandeweege Sander, Verstraelen Hans
Faculty of Medicine and Health Sciences Ghent University Ghent Belgium.
Department of Obstetrics & Gynaecology Ghent University Hospital Ghent Belgium.
Skin Health Dis. 2023 Sep 4;3(5):e281. doi: 10.1002/ski2.281. eCollection 2023 Oct.
Women with vulvar lichen sclerosus (vLS) often express their concern over disease course, treatment, and complications relating to vLS in pregnancy and following childbirth. We used such patient concerns as study objectives in a systematic literature research. Although few, mostly low-quality studies have been published on that matter, and albeit the vast majority of women will have stable vLS during pregnancy, available data also suggest that in a small but significant proportion of patients, pregnancy and delivery may complicate the course of vLS and vice versa.
患有外阴硬化性苔藓(vLS)的女性常常表达她们对疾病进程、治疗以及与孕期和产后vLS相关并发症的担忧。在一项系统性文献研究中,我们将此类患者的担忧作为研究目标。尽管关于该问题的研究发表得很少,且大多质量不高,并且尽管绝大多数女性在孕期vLS病情会保持稳定,但现有数据也表明,在一小部分但比例显著的患者中,怀孕和分娩可能会使vLS病程复杂化,反之亦然。