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妊娠期外阴硬化性苔藓:未满足的需求及系统评价

Vulvar lichen sclerosus in pregnancy: Unaddressed needs and systematic review.

作者信息

Debaene Britt, Vandeweege Sander, Verstraelen Hans

机构信息

Faculty of Medicine and Health Sciences Ghent University Ghent Belgium.

Department of Obstetrics & Gynaecology Ghent University Hospital Ghent Belgium.

出版信息

Skin Health Dis. 2023 Sep 4;3(5):e281. doi: 10.1002/ski2.281. eCollection 2023 Oct.

Abstract

Women with vulvar lichen sclerosus (vLS) often express their concern over disease course, treatment, and complications relating to vLS in pregnancy and following childbirth. We used such patient concerns as study objectives in a systematic literature research. Although few, mostly low-quality studies have been published on that matter, and albeit the vast majority of women will have stable vLS during pregnancy, available data also suggest that in a small but significant proportion of patients, pregnancy and delivery may complicate the course of vLS and vice versa.

摘要

患有外阴硬化性苔藓(vLS)的女性常常表达她们对疾病进程、治疗以及与孕期和产后vLS相关并发症的担忧。在一项系统性文献研究中,我们将此类患者的担忧作为研究目标。尽管关于该问题的研究发表得很少,且大多质量不高,并且尽管绝大多数女性在孕期vLS病情会保持稳定,但现有数据也表明,在一小部分但比例显著的患者中,怀孕和分娩可能会使vLS病程复杂化,反之亦然。

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本文引用的文献

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Vulvar lichen sclerosus in women of reproductive age.育龄期女性的外阴硬化性苔藓
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Lichen sclerosus - the course during pregnancy and effect on delivery.硬化性苔藓——孕期病程及对分娩的影响。
J Eur Acad Dermatol Venereol. 2019 Dec;33(12):e466-e468. doi: 10.1111/jdv.15788. Epub 2019 Jul 22.
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Lichen sclerosus in pregnancy: A review of 33 cases.妊娠期硬化性苔藓:33例病例回顾
Aust N Z J Obstet Gynaecol. 2018 Dec;58(6):686-689. doi: 10.1111/ajo.12812. Epub 2018 Jun 19.
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Lichen sclerosus in pregnancy: presentation of two cases.妊娠性硬斑病:两例病例报告。
J Low Genit Tract Dis. 1999 Oct;3(4):260-3. doi: 10.1046/j.1526-0976.1999.34008.x.

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