与白癜风相关的变体。

variant associated with vitiligo.

作者信息

Li Fucheng, Liao Can, Li Ru, Zhang Yongling, Jing Xiangyi, Li Dongzhi, Deng Weiping

机构信息

Department of Prenatal Diagnostic Center Guangzhou Women and Children's Medical Center Guangzhou Medical University Guangzhou China.

Department of Dermatology Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences) Southern Medical University Guangzhou China.

出版信息

Skin Health Dis. 2023 Aug 16;3(5):e278. doi: 10.1002/ski2.278. eCollection 2023 Oct.

DOI:10.1002/ski2.278

PMID:37799362

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10549816/

Abstract

The manuscript addresses an important topic: genetic analysis of Vitiligo. Vitiligo is a complicated condition and the genetic factors account for 80% of the risk. Linkage analysis for a four generations Chinese family identified 16p13.3p13.2 as the susceptibility locus of vitiligo, whole exome sequencing then identified PDIA2 as the new candidate gene. The association between the candidate gene and vitiligo requires further investigation.

摘要