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临床之星专栏:老年急诊科患者处方开具方面的实践变革进展

Clin-STAR corner: Practice changing advances in prescribing for geriatric emergency department patients.

作者信息

Goldberg Elizabeth M, Dresden Scott M, Carpenter Christopher R

机构信息

Department of Emergency Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA.

School of Medicine Department of Emergency Medicine, Northwestern University, Chicago, Illinois, USA.

出版信息

J Am Geriatr Soc. 2023 Dec;71(12):3686-3691. doi: 10.1111/jgs.18619. Epub 2023 Oct 6.

DOI:10.1111/jgs.18619
PMID:37801018
Abstract

Reducing adverse drug events among older adults in heterogeneous and often chaotic emergency department (ED) settings requires a multidisciplinary approach. Recent research evaluates the impact of multicomponent protocols designed to reduce ED physician prescribing of potentially inappropriate medications (PIMs), including transdisciplinary training and leveraging electronic health records to provide real-time alternative safer pharmaceuticals while providing personalized feedback to prescribers. Most new research is not randomized trial data. Although this current research does not consistently demonstrate a reduction in the prescribing of PIMs, these studies provide a foundation for emergency medicine healthcare teams, geriatricians, and pharmacists to collaborate with health informatics to continue advancing the frontiers of safer medication prescribing during episodes of acute care.

摘要

在异质性且通常混乱的急诊科环境中减少老年人的药物不良事件需要采取多学科方法。最近的研究评估了多组分方案的影响,这些方案旨在减少急诊科医生开具潜在不适当药物(PIMs)的情况,包括跨学科培训以及利用电子健康记录提供实时替代的更安全药物,同时向开处方者提供个性化反馈。大多数新研究并非随机试验数据。尽管当前研究并未始终证明PIMs的处方量有所减少,但这些研究为急诊医学医疗团队、老年病医生和药剂师与健康信息学合作提供了基础,以便在急性护理期间继续推进更安全药物处方的前沿领域。

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引用本文的文献

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Potentially inappropriate polypharmacy is an important predictor of 30-day emergency hospitalisation in older adults: a machine learning feature validation study.潜在不适当的多重用药是老年人30天内紧急住院的重要预测因素:一项机器学习特征验证研究。
Age Ageing. 2025 May 31;54(6). doi: 10.1093/ageing/afaf156.
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Emergency Department Programs to Support Medication Safety in Older Adults: A Systematic Review and Meta-Analysis.支持老年人用药安全的急诊科项目:系统评价与荟萃分析
JAMA Netw Open. 2025 Mar 3;8(3):e250814. doi: 10.1001/jamanetworkopen.2025.0814.