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经皮肾镜取石术后内镜与 CT 评估结石清除状态的比较。

Comparison of endoscopic versus CT assessment of stone-free status after percutaneous nephrolithotomy (PCNL).

机构信息

Department of Urology and Urologic Surgery, University Medical Center Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.

出版信息

Urolithiasis. 2023 Oct 6;51(1):120. doi: 10.1007/s00240-023-01495-7.

Abstract

This study is aimed to determine whether postoperative low dose computed tomography (LDCT) imaging is necessary after percutaneous nephrolithotomy (PCNL), or the surgeon's intraoperative assessment of residual fragments (RF) is sufficient and avoidance of postoperative imaging with reduction of radiation exposure can be achieved. Data of all 610 patients who underwent PCNL in prone position in our institution from February 2009 to September 2020 was collected. Parameters such as age, gender, BMI, ASA-Classification, stone related parameters and the surgeon's assessment of stone-free status were analyzed. The LDCT performed postoperatively was compared to the intraoperative assessment of the surgeon regarding RF. The mean age of patients was 52.82 years; the mean BMI was 28.18 kg/m. In 418 cases, the surgeon made a clear statement about the presence of RF and postoperative LDCT was carried out. The discrepancy between the two methods (surgeon´s assessment vs. LDCT) was significant at p < 0.0001. The sensitivity, specificity, positive and negative predictive value of the surgeon when assessing RF were 24.05%, 99.45%, 98.28% and 50%. Stone free rate (SFR) after primary PCNL was 45.57%. The overall SFR at discharge was 96.23%. Although the surgeon´s assessment of RF was reliable, postoperative LDCT imaging should still be performed if endoscopic stone clearance is suspected due to the high false negative rate and the low negative predictive value. The optimal timing of postoperative imaging following PCNL remains unclear.

摘要

本研究旨在确定经皮肾镜碎石取石术(PCNL)后是否需要进行低剂量计算机断层扫描(LDCT)成像,或者术者术中对残留结石(RF)的评估是否足够,是否可以避免术后成像以减少辐射暴露。收集了 2009 年 2 月至 2020 年 9 月在我院接受 PCNL 治疗的 610 例患者的所有数据。分析了患者的年龄、性别、BMI、ASA 分级、结石相关参数以及术者对无结石状态的评估。比较了术后行 LDCT 与术者对 RF 的术中评估。患者的平均年龄为 52.82 岁;平均 BMI 为 28.18 kg/m。在 418 例患者中,术者明确表示存在 RF,并进行了术后 LDCT。两种方法(术者评估与 LDCT)之间的差异具有统计学意义(p<0.0001)。术者评估 RF 时的灵敏度、特异度、阳性预测值和阴性预测值分别为 24.05%、99.45%、98.28%和 50%。初次 PCNL 后的无石率(SFR)为 45.57%。出院时总体 SFR 为 96.23%。尽管术者对 RF 的评估是可靠的,但如果怀疑内镜下结石清除不彻底,仍应进行术后 LDCT 成像,因为其假阴性率高,阴性预测值低。PCNL 后术后成像的最佳时机仍不清楚。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/979c/10558392/54bd33f040c1/240_2023_1495_Fig1_HTML.jpg

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