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可视化冠状动脉闭塞的灌注不良效应,作为局限型主动脉夹层的后遗症。

Visualizing the malperfusion effect of coronary occlusion as a sequela of limited type A aortic dissection.

机构信息

Washington University School of Medicine, St. Louis, MO, USA.

Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S. Kingshighway Blvd, Campus Box, St. Louis, MO, 8131, USA.

出版信息

Emerg Radiol. 2023 Dec;30(6):801-805. doi: 10.1007/s10140-023-02173-2. Epub 2023 Oct 6.

DOI:10.1007/s10140-023-02173-2
PMID:37801151
Abstract

Limited type A aortic dissection (LTAAD) is a rare subtype of dissection that is confined within a well-defined border of the ascending aorta. These dissections may occur in the remaining native portion of the aortic root following aortic root replacement and can be complicated by malperfusion syndrome-a syndrome where dissections compromise the aortic branches and lead to end-organ ischemia. Because LTAAD is confined within the ascending aorta, malperfusion syndrome may preferentially affect the coronary arteries resulting in coronary malperfusion, myocardial infarction, and increased mortality. We report a case of LTAAD and malperfusion syndrome of the left main coronary artery which resulted in inadequate contrast opacification of the aorta and failure of the dissection protocol to trigger on computed tomography (CT). Upon further evaluation of the situation, the radiologist oversaw the manual triggering of CT acquisitions which yielded an actionable CT at 6 minutes post-contrast and real-time visualization of the patient's developing cardiac ischemia.

摘要

局限性升主动脉夹层(LTAAD)是一种罕见的夹层亚型,局限于升主动脉的明确边界内。这些夹层可能发生在主动脉根部置换后剩余的原生主动脉根部部分,并可能因灌注不良综合征而复杂化-夹层会影响主动脉分支并导致终末器官缺血。由于 LTAAD 局限于升主动脉,灌注不良综合征可能优先影响冠状动脉,导致冠状动脉灌注不良、心肌梗死和死亡率增加。我们报告了一例 LTAAD 和左主干冠状动脉灌注不良综合征,导致主动脉对比度不足,并且 CT 扫描未触发夹层协议。在进一步评估这种情况时,放射科医生监督了 CT 采集的手动触发,在造影后 6 分钟获得了可操作的 CT,并实时观察到患者的心脏缺血情况。

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本文引用的文献

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Outcomes of hemi- vs. total arch replacement in acute type A aortic dissection: A systematic review and meta-analysis.急性A型主动脉夹层半弓置换与全弓置换的疗效:一项系统评价和荟萃分析。
Front Cardiovasc Med. 2022 Sep 27;9:988619. doi: 10.3389/fcvm.2022.988619. eCollection 2022.
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Computed tomographic evaluation of myocardial ischemia.
心肌缺血的计算机断层扫描评估
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Type A aortic dissection complicated by malperfusion syndrome.A型主动脉夹层合并灌注不良综合征。
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Early reperfusion strategy improves the outcomes of surgery for type A acute aortic dissection with malperfusion.早期再灌注策略可改善合并灌注不良的急性 A 型主动脉夹层手术的结局。
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8
A type A aortic dissection missed by non-cardiac gated contrast-enhanced computed tomography due to an aortic root dissection flap masquerading as an aortic valve apparatus: a case report.一例A型主动脉夹层因主动脉根部夹层瓣伪装成主动脉瓣装置而被非心脏门控对比增强计算机断层扫描漏诊:病例报告
J Med Case Rep. 2013 Dec 30;7:285. doi: 10.1186/1752-1947-7-285.
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Coronary malperfusion due to type A aortic dissection: mechanism and surgical management.A型主动脉夹层导致的冠状动脉灌注不良:机制与外科治疗
Ann Thorac Surg. 2003 Nov;76(5):1471-6; discussion 1476. doi: 10.1016/s0003-4975(03)00899-3.
10
Predicting death in patients with acute type a aortic dissection.预测急性A型主动脉夹层患者的死亡情况。
Circulation. 2002 Jan 15;105(2):200-6. doi: 10.1161/hc0202.102246.