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胸腺的临床和诊断影像学评价:从与年龄相关的变化到胸腺瘤,以及其间的一切。

Review of clinical and diagnostic imaging of the thymus: from age-related changes to thymic tumors and everything in between.

机构信息

Department of Radiology, St. Luke's International Hospital, 9-1 Akashi-Cho, Chuo-Ku, Tokyo, 104-8560, Japan.

出版信息

Jpn J Radiol. 2024 Mar;42(3):217-234. doi: 10.1007/s11604-023-01497-w. Epub 2023 Oct 6.

DOI:10.1007/s11604-023-01497-w
PMID:37801191
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10899275/
Abstract

The thymus, a primary lymphoid organ of the immune system, undergoes several changes due to a variety of reasons, ranging from aging to pathological conditions. These changes can make distinguishing between benign and neoplastic changes in the thymus challenging, thereby complicating the histopathological diagnoses of thymic tumors. Moreover, most patients with thymic tumors are asymptomatic at the time of diagnosis. Therefore, imaging plays an extremely important role in the evaluation of thymic lesions. In this review, we introduced the imaging characteristics of the thymus, ranging from benign findings, such as normal maturation and benign lesions, to neoplasms.

摘要

胸腺是免疫系统的主要淋巴器官,由于多种原因,包括衰老和病理状况等,会发生多种变化。这些变化使得区分胸腺中的良性和肿瘤性改变具有挑战性,从而使胸腺瘤的组织病理学诊断变得复杂。此外,大多数胸腺瘤患者在诊断时无症状。因此,影像学在评估胸腺病变中起着极其重要的作用。在这篇综述中,我们介绍了胸腺的影像学特征,包括良性表现,如正常成熟和良性病变,以及肿瘤。

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本文引用的文献

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The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms.《世界卫生组织造血与淋巴组织肿瘤分类》第五版:淋巴肿瘤。
Leukemia. 2022 Jul;36(7):1720-1748. doi: 10.1038/s41375-022-01620-2. Epub 2022 Jun 22.
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The 2021 WHO Classification of Tumors of the Thymus and Mediastinum: What Is New in Thymic Epithelial, Germ Cell, and Mesenchymal Tumors?2021 年世界卫生组织胸腺和纵隔肿瘤分类:胸腺上皮性、生殖细胞性和间叶性肿瘤有哪些新变化?
J Thorac Oncol. 2022 Feb;17(2):200-213. doi: 10.1016/j.jtho.2021.10.010. Epub 2021 Oct 22.
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Mediastinal Germ Cell Tumors: A Review and Update on Pathologic, Clinical, and Molecular Features.
纵隔生殖细胞肿瘤:病理、临床和分子特征的综述与更新。
Adv Anat Pathol. 2021 Sep 1;28(5):335-350. doi: 10.1097/PAP.0000000000000304.
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Klinefelter syndrome and germ cell tumors: review of the literature.克兰费尔特综合征与生殖细胞肿瘤:文献综述
Int J Pediatr Endocrinol. 2020;2020:18. doi: 10.1186/s13633-020-00088-0. Epub 2020 Sep 30.
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Anterior mediastinal lesions: CT and MRI features and differential diagnosis.前纵隔病变:CT 和 MRI 特征及鉴别诊断。
Jpn J Radiol. 2021 Feb;39(2):101-117. doi: 10.1007/s11604-020-01031-2. Epub 2020 Sep 2.
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Medicine (Baltimore). 2015 Jun;94(25):e987. doi: 10.1097/MD.0000000000000987.
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A modern definition of mediastinal compartments.纵隔间隙的现代定义。
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