Pathology Unit, Department of Laboratories, Bambino Gesu Children's Hospital, IRCCS, Rome, Italy.
Department of Pathology, University of Miami, Miami, FL, USA.
Leukemia. 2022 Jul;36(7):1720-1748. doi: 10.1038/s41375-022-01620-2. Epub 2022 Jun 22.
We herein present an overview of the upcoming 5 edition of the World Health Organization Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms. Myeloid and histiocytic neoplasms will be presented in a separate accompanying article. Besides listing the entities of the classification, we highlight and explain changes from the revised 4 edition. These include reorganization of entities by a hierarchical system as is adopted throughout the 5 edition of the WHO classification of tumours of all organ systems, modification of nomenclature for some entities, revision of diagnostic criteria or subtypes, deletion of certain entities, and introduction of new entities, as well as inclusion of tumour-like lesions, mesenchymal lesions specific to lymph node and spleen, and germline predisposition syndromes associated with the lymphoid neoplasms.
我们在此概述即将发布的第五版世界卫生组织血液淋巴肿瘤分类,重点介绍淋巴肿瘤。髓系和组织细胞肿瘤将在另一篇伴随文章中介绍。除了列出分类实体外,我们还强调并解释了与修订后的第四版相比的变化。这些变化包括通过在整个第五版世界卫生组织所有器官系统肿瘤分类中采用的层次系统对实体进行重组、对某些实体的命名进行修改、修改诊断标准或亚型、删除某些实体以及引入新实体,以及纳入肿瘤样病变、淋巴结和脾脏特有的间叶病变以及与淋巴肿瘤相关的种系易感性综合征。
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