Southwest Center for Occupational and Environmental Health, Department of Epidemiology, Human Genetics and Environmental Sciences, The University of Texas Health Science Center at Houston (UTHealth Houston) School of Public Health, Houston, Texas (J.P., A.C., L.W.W., G.L.D.); Center for Pediatric Population Health, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston (UTHealth Houston), Dallas, Texas (J.P.); Southwest Center for Occupational and Environmental Health, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health in San Antonio, The University of Texas Health Science Center at Houston (UTHealth Houston), San Antonio, Texas (D.G.R.d.P.); Center for Research in Occupational Health, Universitat Pompeu Fabra, Barcelona, Spain (D.G.R.d.P., G.L.D.); CIBER Epidemiología y Salud Pública, Madrid, Spain (D.G.R.d.P., G.L.D.); Department of Epidemiology, Human Genetics and Environmental Sciences, The University of Texas Health Science Center at Houston (UTHealth Houston) School of Public Health, Houston, Texas (L.E.M., R.P.); Department of Epidemiology and Biostatistics, Temple University College of Public Health, Philadelphia, Pennsylvania (I.H.); Research in Patient Services, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio (L.P.); Smith Scientific LLC, Houston, Texas (S.C.); Center for Research in Environmental Epidemiology (CREAL), Barcelona, Spain ( J.-P.Z.); Respiratory Health Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia (P.K.H.); and Department of Biostatistics and Data Science, The University of Texas Health Science Center at Houston (UTHealth Houston) School of Public Health, Houston, Texas (J.D.L.R.).
J Occup Environ Med. 2024 Jan 1;66(1):28-34. doi: 10.1097/JOM.0000000000002990. Epub 2023 Oct 6.
Health care workers are at risk for work-related asthma, which may be affected by changes in cleaning practices. We examined associations of cleaning tasks and products with work-related asthma in health care workers in 2016, comparing them with prior results from 2003.
We estimated asthma prevalence by professional group and explored associations of self-reported asthma with job-exposure matrix-based cleaning tasks/products in a representative Texas sample of 9914 physicians, nurses, respiratory/occupational therapists, and nurse aides.
Response rate was 34.8% (n = 2421). The weighted prevalence rates of physician-diagnosed (15.3%), work-exacerbated (4.1%), and new-onset asthma (6.7%) and bronchial hyperresponsiveness symptoms (31.1%) were similar to 2003. New-onset asthma was associated with building surface cleaning (odds ratio [OR], 1.91; 95% confidence interval [CI], 1.10-3.33), use of ortho-phthalaldehyde (OR, 1.77; 95% CI, 1.15-2.72), bleach/quaternary compounds (OR, 1.91; 95% CI, 1.10-3.33), and sprays (OR, 1.97; 95% CI, 1.12-3.47).
Prevalence of asthma/bronchial hyperresponsiveness seems unchanged, whereas associations of new-onset asthma with exposures to surface cleaning remained, and decreased for instrument cleaning.
医护人员面临与工作相关的哮喘风险，而这可能受到清洁工作方式变化的影响。我们研究了 2016 年医护人员的清洁任务和产品与工作相关哮喘之间的关联，并将其与 2003 年的先前结果进行了比较。
我们根据专业组别估计了哮喘的患病率，并在德克萨斯州具有代表性的 9914 名医生、护士、呼吸/职业治疗师和护士助理样本中，利用基于职业暴露矩阵的清洁任务/产品，探索了自我报告哮喘与工作相关哮喘之间的关联。
应答率为 34.8%（n=2421）。经加权后的医生诊断哮喘（15.3%）、工作加重哮喘（4.1%）、新发哮喘（6.7%）和支气管高反应性症状（31.1%）的患病率与 2003 年相似。新发哮喘与建筑物表面清洁（比值比[OR]，1.91；95%置信区间[CI]，1.10-3.33）、使用邻苯二甲醛（OR，1.77；95% CI，1.15-2.72）、含氯/季铵化合物（OR，1.91；95% CI，1.10-3.33）和喷雾剂（OR，1.97；95% CI，1.12-3.47）有关。
哮喘/支气管高反应性的患病率似乎保持不变，而新发哮喘与表面清洁暴露的关联仍然存在，与仪器清洁的关联则有所下降。
