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使用电子鼻和人工智能进行前列腺癌检测,以进行高概率评估。

Prostate cancer detection using e-nose and AI for high probability assessment.

机构信息

Sensor and Magnetism Group, Institut de Recerca Per a La Gestió Integrada de Zones Costaneres (IGIC), Campus de Gandia, Universitat Politecnica de Valencia, Paranimf 1, Grao de Gandia, 46000, Valencia, Spain.

Educacion, Conselleria de Educacion, Cultura y Deporte, Av. de Campanar, 32, 46015, Valencia, Spain.

出版信息

BMC Med Inform Decis Mak. 2023 Oct 6;23(1):205. doi: 10.1186/s12911-023-02312-2.

DOI:10.1186/s12911-023-02312-2
PMID:37803440
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10559535/
Abstract

This research aims to develop a diagnostic tool that can quickly and accurately detect prostate cancer using electronic nose technology and a neural network trained on a dataset of urine samples from patients diagnosed with both prostate cancer and benign prostatic hyperplasia, which incorporates a unique data redundancy method. By analyzing signals from these samples, we were able to significantly reduce the number of unnecessary biopsies and improve the classification method, resulting in a recall rate of 91% for detecting prostate cancer. The goal is to make this technology widely available for use in primary care centers, to allow for rapid and non-invasive diagnoses.

摘要

本研究旨在开发一种诊断工具,该工具使用电子鼻技术和基于前列腺癌和良性前列腺增生患者尿液样本数据集训练的神经网络,结合独特的数据冗余方法,快速、准确地检测前列腺癌。通过分析这些样本的信号,我们能够显著减少不必要的活检数量并改进分类方法,使前列腺癌检测的召回率达到 91%。目标是使这项技术在初级保健中心广泛使用,以实现快速、无创诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eafa/10559535/fee8c0912cf8/12911_2023_2312_Fig7_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eafa/10559535/ad77235ae683/12911_2023_2312_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eafa/10559535/40c86d93dcee/12911_2023_2312_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eafa/10559535/ec8fd0c7c736/12911_2023_2312_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eafa/10559535/05aecf87fd37/12911_2023_2312_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eafa/10559535/bd9fc51a6d87/12911_2023_2312_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eafa/10559535/17f5f763b13d/12911_2023_2312_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eafa/10559535/fee8c0912cf8/12911_2023_2312_Fig7_HTML.jpg

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Machine learning phenomics (MLP) combining deep learning with time-lapse-microscopy for monitoring colorectal adenocarcinoma cells gene expression and drug-response.机器学习表型学(MLP)将深度学习与延时显微镜相结合,用于监测结直肠腺癌细胞的基因表达和药物反应。
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Deciphering Cancer Cell Behavior From Motility and Shape Features: Peer Prediction and Dynamic Selection to Support Cancer Diagnosis and Therapy.
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Serial Percent Free Prostate Specific Antigen in Combination with Prostate Specific Antigen for Population Based Early Detection of Prostate Cancer.基于人群的前列腺癌早期检测中,游离前列腺特异性抗原百分比与前列腺特异性抗原的连续检测。
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