Sdao-Jarvie K, Vogel-Sprott M
Drug Alcohol Depend. 1986 Sep;18(1):23-30. doi: 10.1016/0376-8716(86)90111-0.
Two groups of six male social drinkers learned a psychomotor skill task and then drank the same dose of ethanol (0.62 g/kg) on each of five sessions. Sessions 1 and 5 provided pre-treatment and post-treatment measures of task performance under ethanol. During treatment sessions 2, 3 and 4, one group (MRBD) mentally rehearsed the task before drinking and the other group (MRAD) mentally rehearsed the task after drinking. On the post-treatment session, the MRAD group was significantly less impaired (i.e. more tolerant) than the MRBD group. Thus, mental rehearsal of a task under ethanol facilitates the development of tolerance to the behavioral effects of the drug.
两组各有六名男性社交饮酒者学习了一项心理运动技能任务,然后在五个疗程中的每个疗程都饮用相同剂量的乙醇(0.62克/千克)。第1和第5疗程提供了乙醇作用下任务表现的治疗前和治疗后测量数据。在第2、3和4个治疗疗程中,一组(MRBD)在饮酒前进行任务的心理预演,另一组(MRAD)在饮酒后进行任务的心理预演。在治疗后疗程中,MRAD组的受损程度明显低于MRBD组(即耐受性更强)。因此,在乙醇作用下对任务进行心理预演有助于形成对药物行为效应的耐受性。