Harvard Medical School, Boston, MA, USA.
Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Curr Cardiol Rep. 2023 Nov;25(11):1611-1622. doi: 10.1007/s11886-023-01973-9. Epub 2023 Oct 7.
Peripheral artery disease (PAD) is an increasingly prevalent but frequently underdiagnosed condition that can be associated with high rates of morbidity and mortality. While an initial noninvasive approach is the cornerstone of management, revascularization is often pursued for patients with treatment-refractory claudication or chronic limb-threatening ischemia (CLTI). In this review, we discuss the current state of endovascular interventions for PAD and explore the many new emerging technologies.
The last decade has resulted in numerous advances in PAD interventions including the ongoing evolution of drug-coated devices, novel approaches to complex lesions, and contemporary evidence from large clinical trials for CLTI. Advances in endovascular management have allowed for increasingly complex lesions to be tackled percutaneously. Future directions for the field include the continued evolution in device technology, continued development of state-of-the-art techniques to revascularization of complex lesions, and increased collaboration between a largely multidisciplinary field.
外周动脉疾病（PAD）是一种日益流行但常被漏诊的疾病，可导致高发病率和死亡率。虽然初始的非侵入性方法是管理的基石，但对于治疗抵抗性跛行或慢性肢体威胁性缺血（CLTI）的患者，常需要进行血运重建。在这篇综述中，我们讨论了 PAD 的血管内介入治疗的现状，并探讨了许多新兴技术。
过去十年中，PAD 介入治疗取得了许多进展，包括药物涂层器械的不断发展、复杂病变的新方法以及 CLTI 的大型临床试验的当代证据。血管内治疗的进步使得越来越复杂的病变可以通过经皮途径进行治疗。该领域的未来发展方向包括器械技术的不断发展、复杂病变血运重建的最新技术的不断发展以及在很大程度上是多学科领域之间的更多合作。
