Department of Immunology, Center of Immunomolecular Engineering, Innovation & Practice Base for Graduate Students Education, Zunyi Medical University, Zunyi City, China.
Department of Immunology, Center of Immunomolecular Engineering, Innovation & Practice Base for Graduate Students Education, Zunyi Medical University, Zunyi City, China.
Clin Microbiol Infect. 2024 Feb;30(2):206-210. doi: 10.1016/j.cmi.2023.09.025. Epub 2023 Oct 5.
Bats have garnered increased attention in the field of life sciences for their typical biological characteristics of carrying a variety of zoonotic viruses without disease, long lifespans, low tumorigenesis rates, and high metabolism. When it was found that bats can carry the rabies virus, over 60 years of research revealed that bats host over 4100 distinct viruses, including Ebola virus and SARS-CoV.
This paper primarily reviews the profiles of zoonotic viruses carried by bats across various regions globally. The review aims to provide a foundation and reference for future research on monitoring zoonotic viruses in diverse global regions and bat species, exploring the coevolutionary relationship between bats and viruses, understanding the tolerance mechanisms of bat B cells, prevention, and treatment of zoonotic diseases caused by bats.
The search used 'bat', 'bats', 'rabies virus', 'Dengue virus', 'West Nile virus', 'Zika virus', 'St. Louis encephalitis virus', 'Japanese encephalitis virus', 'Hantavirus', 'Novel hantavirus', 'Rift Valley fever virus', 'Crimean Congo hemorrhagic fever virus', 'Paramyxovirus', 'Nipah virus', 'Hendra virus', 'Menangle virus', 'Tioman virus', 'Marburg Virus', 'Bombali virus', 'Ebola virus', 'Influenza A virus', 'coronavirus', 'Hepatitis B virus', and 'Hepatitis E virus' as text in PubMed.
A total of 147 references were obtained. Surveys on severe zoonotic virus carriage have been limited to only 83 bat species belonging to nine families, which are distributed all over the world. We also briefly describe the antibody responses and B-cell molecules in bats.
Several viruses have been found in different species of bats. This suggests that bats may be important hosts for future viral infectious diseases. Particularly in recent years, the close correlation between human infection pandemics caused by coronaviruses and bats highlights the pressing need to comprehend the species, tolerance, and coevolutionary mechanisms of zoonotic viruses carried by different bat species.
蝙蝠因其携带多种人畜共患病毒而无疾病、寿命长、肿瘤发生率低、代谢率高的典型生物学特性，在生命科学领域受到越来越多的关注。当发现蝙蝠可以携带狂犬病病毒时，经过 60 多年的研究表明，蝙蝠携带的病毒超过 4100 种，包括埃博拉病毒和 SARS-CoV。
本文主要综述了全球不同地区蝙蝠携带的人畜共患病毒的特征。该综述旨在为未来监测不同地区和蝙蝠物种的人畜共患病毒、探索蝙蝠与病毒的协同进化关系、了解蝙蝠 B 细胞的耐受机制、预防和治疗蝙蝠引起的人畜共患疾病提供基础和参考。
在 PubMed 中，使用“bat”、“bats”、“rabies virus”、“Dengue virus”、“West Nile virus”、“Zika virus”、“St. Louis encephalitis virus”、“Japanese encephalitis virus”、“Hantavirus”、“Novel hantavirus”、“Rift Valley fever virus”、“Crimean Congo hemorrhagic fever virus”、“Paramyxovirus”、“Nipah virus”、“Hendra virus”、“Menangle virus”、“Tioman virus”、“Marburg Virus”、“Bombali virus”、“Ebola virus”、“Influenza A virus”、“coronavirus”、“Hepatitis B virus”和“Hepatitis E virus”作为文本进行了搜索。
共获得 147 篇参考文献。对严重人畜共患病毒携带情况的调查仅限于分布在世界各地的 9 个科的 83 种蝙蝠。我们还简要描述了蝙蝠中的抗体反应和 B 细胞分子。
在不同种类的蝙蝠中发现了几种病毒。这表明蝙蝠可能是未来病毒性传染病的重要宿主。特别是近年来，冠状病毒引起的人类感染大流行与蝙蝠之间的密切关联，突显了迫切需要了解不同蝙蝠物种携带的人畜共患病毒的种类、耐受性和协同进化机制。
