Molecular Biology Unit, Faculty of Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India.
Dr. B R Ambedkar Center for Biomedical Research, University of Delhi (North Campus), New Delhi, 110007, India.
Future Microbiol. 2024 Jun 12;19(9):841-856. doi: 10.2217/fmb-2023-0233. Epub 2024 Apr 22.
The emergence of highly zoonotic viral infections has propelled bat research forward. The viral outbreaks including Hendra virus, Nipah virus, Marburg virus, Ebola virus, Rabies virus, Middle East respiratory syndrome coronavirus, SARS-CoV and the latest SARS-CoV-2 have been epidemiologically linked to various bat species. Bats possess unique immunological characteristics that allow them to serve as a potential viral reservoir. Bats are also known to protect themselves against viruses and maintain their immunity. Therefore, there is a need for in-depth understanding into bat-virus biology to unravel the major factors contributing to the coexistence and spread of viruses.
高致病性人畜共患病毒感染的出现推动了蝙蝠研究的发展。亨德拉病毒、尼帕病毒、马尔堡病毒、埃博拉病毒、狂犬病病毒、中东呼吸综合征冠状病毒、严重急性呼吸综合征冠状病毒和最新的严重急性呼吸综合征冠状病毒-2 等病毒疫情已在流行病学上与各种蝙蝠物种相关联。蝙蝠具有独特的免疫特征，使它们成为潜在的病毒储存库。蝙蝠也被认为能够保护自己免受病毒侵害并保持免疫力。因此，需要深入了解蝙蝠-病毒生物学，以揭示导致病毒共存和传播的主要因素。
