Suppr超能文献

钝性创伤性主动脉损伤II级(SVS分级)非手术治疗的系统评价与Meta分析

Systematic Review and Meta-Analysis of Nonoperative Management for SVS Grade II Blunt Traumatic Aortic Injury.

作者信息

De Freitas Simon, Joyce Doireann, Yang Yang, Dunphy Kaitlyn, Walsh Stewart, Fatima Javairiah

机构信息

Department of Vascular Surgery, Georgetown University Hospital, MedStar Health, Washington, DC.

Department of Vascular Surgery, Galway University Hospital, Galway, Republic of Ireland.

出版信息

Ann Vasc Surg. 2024 Jan;98:220-227. doi: 10.1016/j.avsg.2023.07.106. Epub 2023 Oct 6.

Abstract

BACKGROUND

Society for Vascular Surgery (SVS) grade II blunt traumatic aortic injury is defined as intramural hematoma with or without external contour abnormality. It is uncertain whether this aortic injury pattern should be treated with endovascular stent-grafting or nonoperative measures. Since the adoption of the SVS Guidelines on endovascular repair of blunt traumatic aortic injury, the practice pattern for management of grade II injuries has been heterogenous. The objective of the study was to report natural history outcomes of grade II blunt traumatic aortic injury.

METHODS

A systematic review of published traumatic aortic injury studies was performed. Online database searches were current to November 2022. Eligible studies included data on aortic injuries that were both managed nonoperatively and classified according to the SVS 2011 Guidelines. Data points on all-cause mortality, aorta-related mortality and early aortic intervention were extracted and underwent meta-analysis. The methodology was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidance.

RESULTS

Thirteen studies were included in the final analysis with a total of 204 cases of SVS grade II blunt traumatic aortic injury treated nonoperatively. The outcomes rates were estimated at 10.4% (95% confidence interval [CI] 6.7%-14.9%) for all-cause mortality, 2.9% (95% CI 1.1%-5.7%) for aorta-related mortality, and 3.3% (95% CI 1.4%-6.2%) for early aortic intervention. The studies included in the analysis were of fair quality with a mean Downs and Black score 15 (±1.8).

CONCLUSIONS

Grade II blunt traumatic aortic injury follows a relatively benign course with few instances of aortic-related mortality. Death in the setting of this injury pattern is more often attributable to sequelae of multisystem trauma and not directly related to aortic injury. The current data support nonoperative management and imaging surveillance for grade II blunt traumatic aortic injury instead of endovascular repair. Longer-term effects on the aorta at the site of injury are unknown.

摘要

背景

血管外科学会(SVS)II级钝性创伤性主动脉损伤定义为伴有或不伴有外部轮廓异常的壁内血肿。目前尚不确定这种主动脉损伤模式应采用血管内支架植入术治疗还是非手术治疗措施。自采用SVS关于钝性创伤性主动脉损伤血管内修复的指南以来,II级损伤的治疗模式一直存在差异。本研究的目的是报告II级钝性创伤性主动脉损伤的自然转归结果。

方法

对已发表的创伤性主动脉损伤研究进行系统综述。在线数据库检索截至2022年11月。符合条件的研究包括非手术治疗且根据SVS 2011指南分类的主动脉损伤数据。提取全因死亡率、主动脉相关死亡率和早期主动脉干预的数据点并进行荟萃分析。该方法按照系统评价和荟萃分析的首选报告项目指南进行。

结果

最终分析纳入了13项研究,共有204例非手术治疗的SVS II级钝性创伤性主动脉损伤病例。全因死亡率估计为10.4%(95%置信区间[CI]6.7%-14.9%),主动脉相关死亡率为2.9%(95%CI 1.1%-5.7%),早期主动脉干预率为3.3%(95%CI 1.4%-6.2%)。分析中纳入的研究质量一般,平均唐斯和布莱克评分为15(±1.8)。

结论

II级钝性创伤性主动脉损伤病程相对良性,主动脉相关死亡率较低。这种损伤模式下的死亡更多归因于多系统创伤的后遗症,而非直接与主动脉损伤相关。目前的数据支持对II级钝性创伤性主动脉损伤进行非手术治疗和影像监测,而非血管内修复。损伤部位对主动脉的长期影响尚不清楚。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验