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双动脉下室间隔缺损:经右垂直腋后线开胸经肺动脉主干行手术闭合是否安全?

Doubly committed ventricular septal defect: Is it safe to perform surgical closure through the pulmonary trunk approached by right vertical axillary thoracotomy?

作者信息

Nguyen Uoc Huu, Nguyen Truong Ly Thinh, Kotani Yasuhiro, Nguyen Mai Tuan, Mai Duyen Dinh, Nguyen Van Anh Thi, Nguyen Nam Trung

机构信息

Department of Surgery, Hanoi Medical University, Hanoi, Vietnam.

Department of Cardiovascular Surgery, Vietnam National Children's Hospital, Hanoi, Vietnam.

出版信息

JTCVS Open. 2023 Jul 6;15:368-373. doi: 10.1016/j.xjon.2023.06.012. eCollection 2023 Sep.

Abstract

OBJECTIVE

This study investigated the safety of performing surgical repair for doubly committed ventricular septal defects by right vertical infra-axillary minithoracotomy (RVIAT).

METHODS

A retrospective comparative study was performed to evaluate the outcomes of patients who underwent doubly committed ventricular septal defects closure from January 2019 to May 2022. Seventy-four patients were enrolled in the study and treated with either the median sternotomy approach (MSA: n = 37) or the RVIAT approach (RVIAT: n = 37).

RESULTS

The median weight and age in the MSA group were significantly lower than those in the RVIAT group (MSA: 6.0 kg [interquartile range] (IQR), 5.2 to 8.7 kg] vs RVIAT: 7.5 kg [IQR, 5.6-14 kg];  = .034 and MSA: 4.9 months [IQR, 3.6-9.4 month] vs 9.6 months [IQR, 5.0-60.4 months];  = .0084). No patients died, and no patients in the RVIAT group required conversion to the MSA approach. The mean prebypass surgical time was longer in the RVIAT group (36.1 ± 8.2 minutes vs 31.8 ± 5.6 minutes;  = .03). There were no significant differences between the 2 groups in cardiopulmonary bypass time, aortic crossclamp time, or operation time. Significantly shorter ventilation times were observed in the RVIAT group (11.9 ± 8.2 hours vs 15.4 ± 6.3 hours;  = .006).

CONCLUSIONS

Closure of doubly committed ventricular septal defects through the pulmonary trunk by the RVIAT approach is feasible and safe, and does not increase the risk of bypass-related complications.

摘要

目的

本研究探讨经右腋下垂直小切口(RVIAT)行双干下型室间隔缺损手术修复的安全性。

方法

进行一项回顾性比较研究,以评估2019年1月至2022年5月期间接受双干下型室间隔缺损封堵术患者的治疗结果。74例患者纳入本研究,分别接受正中胸骨切开术(MSA组:n = 37)或RVIAT手术(RVIAT组:n = 37)。

结果

MSA组患者的体重中位数和年龄显著低于RVIAT组(MSA组:6.0 kg[四分位间距](IQR),5.2至8.7 kg],而RVIAT组:7.5 kg[IQR,5.6 - 14 kg];P = 0.034;MSA组:4.9个月[IQR,3.6 - 9.4个月],而RVIAT组:9.6个月[IQR,5.0 - 60.4个月];P = 0.0084)。无患者死亡,RVIAT组无患者需要转为MSA手术方式。RVIAT组体外循环前手术时间较长(36.1±8.2分钟 vs 31.8±5.6分钟;P = 0.03)。两组在体外循环时间、主动脉阻断时间或手术时间方面无显著差异。RVIAT组通气时间显著缩短(11.9±8.2小时 vs 15.4±6.3小时;P = 0.006)。

结论

经RVIAT入路经肺动脉主干闭合双干下型室间隔缺损是可行且安全的,不会增加体外循环相关并发症的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b78d/10556957/eb1b21a925a7/ga1.jpg

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