Cuko Besart, Baudo Massimo, Beurton Antoine, Busuttil Olivier, Pernot Mathieu
Department of Cardiology and Cardio-Vascular Surgery, Hopital Cardiologique de Haut-Leveque, Pessac, FRA.
Department of Cardiac Surgery, ASST Spedali Civili di Brescia, University of Brescia, Brescia, ITA.
Cureus. 2023 Sep 4;15(9):e44688. doi: 10.7759/cureus.44688. eCollection 2023 Sep.
In the current era of improved survival after orthotopic heart transplantation, post-transplant valve dysfunction is not an uncommon occurrence. The first treatment is medical management, but when it fails, surgery, possibly as retransplantation, may be needed. However, due to the scarcity of donor hearts, efforts are being made on the preservation of the cardiac allograft function by conventional operations in lieu of retransplantation. In this case report, we present a patient developing severe aortic valve insufficiency and moderate-to-severe functional tricuspid valve insufficiency five years after cardiac transplant, leading to progressive clinical deterioration and heart failure symptoms. The aortic valve was replaced with an Edwards Inspiris Resilia Nr. 23 biological prosthesis, and the tricuspid valve was repaired with a Medtronic Contour 3D Nr. 28 annuloplasty. The postoperative course was uneventful, and the patient remained well six months after her reintervention. In the literature, cases of patients undergoing valve operations following their heart transplants have already been described. However, to the best of our knowledge, this is the first case report describing a concomitant procedure of aortic valve replacement and tricuspid valve repair in an adult patient occurring five years after her cardiac transplant.
在当前原位心脏移植后生存率提高的时代,移植后瓣膜功能障碍并非罕见。首先采用药物治疗,但治疗失败时,可能需要进行手术,甚至再次移植。然而,由于供体心脏稀缺,人们正努力通过常规手术来保留心脏移植功能,以替代再次移植。在本病例报告中,我们介绍了一名心脏移植术后五年出现严重主动脉瓣关闭不全和中重度功能性三尖瓣关闭不全的患者,导致临床症状逐渐恶化和出现心力衰竭症状。主动脉瓣被替换为23号爱德华兹Inspiris Resilia生物假体,三尖瓣用28号美敦力Contour 3D瓣环成形术进行修复。术后过程顺利,再次干预后六个月患者情况良好。在文献中,已经描述了心脏移植后接受瓣膜手术的患者病例。然而,据我们所知,这是第一例描述成年患者心脏移植五年后同时进行主动脉瓣置换和三尖瓣修复手术的病例报告。